Pathogenesis of Bronchiectasis

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50 Scopus citations

Abstract

Cystic fibrosis (CF) typically follows a more severe clinical course than non-CF bronchiectasis. Despite this recognized difference, the underpinnings of respiratory biology support a common pathogeneses of the anatomic deformations of bronchiectasis. This article reviews the observed manifestations among the related diseases of bronchiectasis and CF and discusses some of their similarities and differences. As more details of the mechanisms of bronchiectasis are unveiled, more parallels among the seemingly disparate causes of CF and non-CF bronchiectasis are recognized. With these insights, more opportunities to halt the vicious circle have become apparent.

Original languageEnglish (US)
Pages (from-to)289-296
Number of pages8
JournalClinics in Chest Medicine
Volume28
Issue number2
DOIs
StatePublished - Jun 2007

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ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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