Patch fluorometry: Shedding new light on ion channels

Jie Zheng

Research output: Contribution to journal › Article

15 Citations (Scopus)

Abstract

Patch fluorometry has emerged as a new approach to the study of the structure-function relationship in membrane-embedded functional ion channels. Simultaneous fluorescent and electrical recordings are achieved from a small number of channels in a cell-free membrane patch, yielding high recording sensitivities. Further improvement of this approach should permit direct observation of the gating motion of a single-channel protein.

Original languageEnglish (US)
Pages (from-to)6-12
Number of pages7
JournalPhysiology
Volume21
Issue number1
DOIs
StatePublished - Feb 2006

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Fluorometry
Ion Channels
Cell Membrane
Observation
Membranes
Proteins

ASJC Scopus subject areas

  • Physiology

Cite this

Patch fluorometry : Shedding new light on ion channels. / Zheng, Jie.

In: Physiology, Vol. 21, No. 1, 02.2006, p. 6-12.

Research output: Contribution to journal › Article

Zheng, J 2006, 'Patch fluorometry: Shedding new light on ion channels', Physiology, vol. 21, no. 1, pp. 6-12. https://doi.org/10.1152/physiol.00041.2005
Zheng J. Patch fluorometry: Shedding new light on ion channels. Physiology. 2006 Feb;21(1):6-12. https://doi.org/10.1152/physiol.00041.2005
Zheng, Jie. / Patch fluorometry : Shedding new light on ion channels. In: Physiology. 2006 ; Vol. 21, No. 1. pp. 6-12.
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