Patch fluorometry: Shedding new light on ion channels

Research output: Contribution to journalArticle

15 Scopus citations

Abstract

Patch fluorometry has emerged as a new approach to the study of the structure-function relationship in membrane-embedded functional ion channels. Simultaneous fluorescent and electrical recordings are achieved from a small number of channels in a cell-free membrane patch, yielding high recording sensitivities. Further improvement of this approach should permit direct observation of the gating motion of a single-channel protein.

Original languageEnglish (US)
Pages (from-to)6-12
Number of pages7
JournalPhysiology
Volume21
Issue number1
DOIs
StatePublished - Feb 2006

ASJC Scopus subject areas

  • Physiology

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