Abstract
Patch fluorometry has emerged as a new approach to the study of the structure-function relationship in membrane-embedded functional ion channels. Simultaneous fluorescent and electrical recordings are achieved from a small number of channels in a cell-free membrane patch, yielding high recording sensitivities. Further improvement of this approach should permit direct observation of the gating motion of a single-channel protein.
Original language | English (US) |
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Pages (from-to) | 6-12 |
Number of pages | 7 |
Journal | Physiology |
Volume | 21 |
Issue number | 1 |
DOIs | |
State | Published - Feb 2006 |
ASJC Scopus subject areas
- Physiology