PARylation: Strengthening the Connection between Cancer and Pluripotency

Wenbin Deng

doi:10.1016/j.stem.2009.09.002

PARylation: Strengthening the Connection between Cancer and Pluripotency

Wenbin Deng

Biochemistry and Molecular Medicine

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Pluripotency and tumorgenicity appear fundamentally linked. Recent investigations into the role of PARylation in chromatin remodeling (Ahel et al., 2009; Gottschalk et al., 2009), combined with the demonstration that p53 serves as a barrier to pluripotency (Banito et al., 2009), further strengthen this connection.

Original language	English (US)
Pages (from-to)	349-350
Number of pages	2
Journal	Cell Stem Cell
Volume	5
Issue number	4
DOIs	https://doi.org/10.1016/j.stem.2009.09.002
State	Published - Oct 2 2009

ASJC Scopus subject areas

Cell Biology
Molecular Medicine
Genetics

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10.1016/j.stem.2009.09.002

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title = "PARylation: Strengthening the Connection between Cancer and Pluripotency",

abstract = "Pluripotency and tumorgenicity appear fundamentally linked. Recent investigations into the role of PARylation in chromatin remodeling (Ahel et al., 2009; Gottschalk et al., 2009), combined with the demonstration that p53 serves as a barrier to pluripotency (Banito et al., 2009), further strengthen this connection.",

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AB - Pluripotency and tumorgenicity appear fundamentally linked. Recent investigations into the role of PARylation in chromatin remodeling (Ahel et al., 2009; Gottschalk et al., 2009), combined with the demonstration that p53 serves as a barrier to pluripotency (Banito et al., 2009), further strengthen this connection.

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JO - Cell Stem Cell

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PARylation: Strengthening the Connection between Cancer and Pluripotency

Abstract

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