Particulate matter, endotoxin, and worker respiratory health on large Californian dairies

Diane C. Mitchell, Tracey L. Armitage, Marc B Schenker, Deborah H Bennett, Daniel J Tancredi, Chelsea Eastman Langer, Stephen J. Reynolds, Greg Dooley, John Mehaffy, Frank M. Mitloehner

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

OBJECTIVE:: To assess respiratory exposures and lung function in a cross-sectional study of California dairy workers. METHODS:: Exposure of 205 dairy and 45 control (vegetable processing) workers to particulate matter and endotoxin was monitored. Pre- and postshift spirometry and interviews were conducted. RESULTS:: Geometric mean inhalable and PM2.5 concentrations were 812 and 35.3 μg/m versus 481.9 and 19.6 μg/m, respectively, for dairy and control workers. Endotoxin concentrations were 329 EU/m or 1122 pmol/m and 13.5 EU/m or 110 pmol/m, respectively, for dairy and control workers. In a mixed-effects model, forced vital capacity decreased across a work shift by 24.5 mL (95% confidence interval, -44.7 to -4.3; P = 0.018) with log10 (total endotoxin) and by 22.0 mL (95% confidence interval, -43.2 to -0.08; P = 0.042) per hour worked. CONCLUSIONS:: Modern California dairy endotoxin exposures and shift length were associated with a mild acute decrease in forced vital capacity.

Original languageEnglish (US)
Pages (from-to)79-87
Number of pages9
JournalJournal of Occupational and Environmental Medicine
Volume57
Issue number1
DOIs
StatePublished - Jan 21 2015

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Particulate Matter
Endotoxins
Vital Capacity
Health
Confidence Intervals
Spirometry
Vegetables
Cross-Sectional Studies
Interviews
Lung

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

Cite this

Particulate matter, endotoxin, and worker respiratory health on large Californian dairies. / Mitchell, Diane C.; Armitage, Tracey L.; Schenker, Marc B; Bennett, Deborah H; Tancredi, Daniel J; Langer, Chelsea Eastman; Reynolds, Stephen J.; Dooley, Greg; Mehaffy, John; Mitloehner, Frank M.

In: Journal of Occupational and Environmental Medicine, Vol. 57, No. 1, 21.01.2015, p. 79-87.

Research output: Contribution to journalArticle

Mitchell, Diane C. ; Armitage, Tracey L. ; Schenker, Marc B ; Bennett, Deborah H ; Tancredi, Daniel J ; Langer, Chelsea Eastman ; Reynolds, Stephen J. ; Dooley, Greg ; Mehaffy, John ; Mitloehner, Frank M. / Particulate matter, endotoxin, and worker respiratory health on large Californian dairies. In: Journal of Occupational and Environmental Medicine. 2015 ; Vol. 57, No. 1. pp. 79-87.
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