OBJECTIVE:: To assess respiratory exposures and lung function in a cross-sectional study of California dairy workers. METHODS:: Exposure of 205 dairy and 45 control (vegetable processing) workers to particulate matter and endotoxin was monitored. Pre- and postshift spirometry and interviews were conducted. RESULTS:: Geometric mean inhalable and PM2.5 concentrations were 812 and 35.3 μg/m versus 481.9 and 19.6 μg/m, respectively, for dairy and control workers. Endotoxin concentrations were 329 EU/m or 1122 pmol/m and 13.5 EU/m or 110 pmol/m, respectively, for dairy and control workers. In a mixed-effects model, forced vital capacity decreased across a work shift by 24.5 mL (95% confidence interval, -44.7 to -4.3; P = 0.018) with log10 (total endotoxin) and by 22.0 mL (95% confidence interval, -43.2 to -0.08; P = 0.042) per hour worked. CONCLUSIONS:: Modern California dairy endotoxin exposures and shift length were associated with a mild acute decrease in forced vital capacity.
|Original language||English (US)|
|Number of pages||9|
|Journal||Journal of Occupational and Environmental Medicine|
|State||Published - Jan 21 2015|
ASJC Scopus subject areas
- Public Health, Environmental and Occupational Health