Particle Toxicities

A. K. Madl, X. Sun, R. M. Silva, T. Kadir, Kent E Pinkerton

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations


This article reviews how different types of airborne particles and fibers can lead to very different biological responses, depending on their physicochemical characteristics, biopersistence, and internal dose. This article will also touch upon the theoretical or known mechanisms by which some airborne particles cause toxicity, including how particle physicochemistry can influence particle deposition and clearance patterns and ultimately lead to different patterns of site-specific or broad-based structural changes in the lungs.

Original languageEnglish (US)
Title of host publicationRespiratory Toxicology
PublisherElsevier Inc.
Number of pages39
ISBN (Electronic)9780081006122
ISBN (Print)9780081006016
StatePublished - Dec 15 2017


  • Ambient particulate matter
  • Asbestos
  • Beryllium
  • Bronchoalveolar duct junction
  • Coal dust
  • Concentrated ambient particles
  • Fibrosis
  • Particle toxicities
  • Respiratory bronchioles
  • Silica

ASJC Scopus subject areas

  • Medicine(all)


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