Particle Toxicities

A. K. Madl, X. Sun, R. M. Silva, T. Kadir, Kent E Pinkerton

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

This article reviews how different types of airborne particles and fibers can lead to very different biological responses, depending on their physicochemical characteristics, biopersistence, and internal dose. This article will also touch upon the theoretical or known mechanisms by which some airborne particles cause toxicity, including how particle physicochemistry can influence particle deposition and clearance patterns and ultimately lead to different patterns of site-specific or broad-based structural changes in the lungs.

Original languageEnglish (US)
Title of host publicationRespiratory Toxicology
PublisherElsevier Inc.
Pages263-301
Number of pages39
Volume15-15
ISBN (Electronic)9780081006122
ISBN (Print)9780081006016
DOIs
StatePublished - Dec 15 2017

Keywords

  • Ambient particulate matter
  • Asbestos
  • Beryllium
  • Bronchoalveolar duct junction
  • Coal dust
  • Concentrated ambient particles
  • Fibrosis
  • Particle toxicities
  • Respiratory bronchioles
  • Silica

ASJC Scopus subject areas

  • Medicine(all)

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  • Cite this

    Madl, A. K., Sun, X., Silva, R. M., Kadir, T., & Pinkerton, K. E. (2017). Particle Toxicities. In Respiratory Toxicology (Vol. 15-15, pp. 263-301). Elsevier Inc.. https://doi.org/10.1016/B978-0-12-801238-3.02084-5