Abstract
for participation in clinical trials (CTs) at the University of California Davis, MIND Institute. We conducted a cross-sectional survey in 100 participants (81 females and 19 males). The participants had high education levels (only 2% had not completed high school), a mean age of 44 years (SD±9.899) and had at least one child with a neurodevelopmental disorder. The diagnosis of Fragile X syndrome (FXS) had a significant association with past participation in CTs (p < 0.001). A statistical significance for age of diagnosis and participation in CTs was also found (z =.2.01, p = 0.045). The motivating factors were to help find cures/treatments for neurodevelopmental disorders and to relieve symptoms related to child's diagnosis. Factors explaining lack of participation, unwillingness to participate or unsure of participation were: lack of information/knowledge about the trials, time commitment to participation (screening, appointments, assessments, laboratory tests, etc.) and low annual household income. These results show that a portion of underrepresented minorities (URM) not participating in CTs are willing to participate and suggests that reducing barriers, particularly lack of knowledge/information and time commitment to trials are needed to improve recruitment.
Original language | English (US) |
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Pages (from-to) | 147-152 |
Number of pages | 6 |
Journal | Intractable and Rare Diseases Research |
Volume | 3 |
Issue number | 4 |
DOIs | |
State | Published - 2014 |
Keywords
- ASD
- autism
- clinical trials
- Fragile X syndrome
- health disparities
- under represent minorities
- URM
ASJC Scopus subject areas
- Medicine(all)