Paper: Evaluation of the toxicity of Adonis aestivalis in sheep

Leslie Woods, Birgit Puschner, M. S. Filigenzi, D. M. Woods, L. W. George

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


To determine the toxicity of Adonis aestivalis (adonis) in sheep, adult Suffolk ewes were administered 1 per cent bodyweight adonis via surgically placed rumen cannulas in an acute, high-dose toxicity study, and 0.2 per cent bodyweight daily in a two-week, low-dose toxicity study. The ewes received cardiac examinations before dosing, 24 and 48 hours after dosing with 1 per cent bodyweight adonis, and after continuous low-dose administration. All the ewes administered adonis had transient sinus arrhythmias after receiving 1 per cent bodyweight adonis. Two of the three ewes had transient reduced fractional shortening after administration with 1 per cent bodyweight adonis; the same two ewes had reduced fractional shortening after the low-dose treatment regimen. No gross or microscopic lesions were seen when the ewes were examined postmortem at the end of the study.

Original languageEnglish (US)
Pages (from-to)49
Number of pages1
JournalVeterinary Record
Issue number2
StatePublished - Jan 15 2011

ASJC Scopus subject areas

  • veterinary(all)


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