Pancreatic neuroendocrine tumors (PNETs)

Rouzbeh Daylami, Dhruvil Shah, Richard J Bold

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Pancreatic neuroendocrine tumors (PNETs) are tumors that arise from hormone-secreting cells of the islets of Langerhans; however, not all tumors will be associated with a clinical syndrome of hormonal hypersecretion. Surgical intervention is guided by overarching principles of functioning/nonfunctioning tumors, extent of disease, and location of the tumor. Even in the setting of advanced disease including hepatic metastasis, surgical intervention may be appropriate and can provide durable periods of disease-free survival. In addition, recent molecular characterization of PNETs has allowed the identification of newer systemic therapies with improving efficacy.

Original languageEnglish (US)
Title of host publicationSurgical Oncology a Practical and Comprehensive Approach
PublisherSpringer New York
Pages563-572
Number of pages10
ISBN (Print)9781493914234, 9781493914227
DOIs
StatePublished - Jan 1 2015

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ASJC Scopus subject areas

  • Medicine(all)

Cite this

Daylami, R., Shah, D., & Bold, R. J. (2015). Pancreatic neuroendocrine tumors (PNETs). In Surgical Oncology a Practical and Comprehensive Approach (pp. 563-572). Springer New York. https://doi.org/10.1007/978-1-4939-1423-4_24