Palliation of malignant oesophageal obstruction by endoscopic alcohol injection

S. C S Chung, H. T. Leong, C. Y C Choi, Joseph Leung, A. K C Li

Research output: Contribution to journalArticle

54 Citations (Scopus)

Abstract

Thirty six-patients with inoperable cancers of the oesophagus or gastric tumour in the cardia were treated by endoscopic alcohol injection. After dilatation using Savary dilators, absolute alcohol was injected in 0.5-1 ml aliquots into protuberant parts using a sclerotherapy needle. The mean volume per session was 7.8 ml. The mean dysphagia score improved from 2.7 before treatment to 1.4 after treatment (p<0.001). Complications included mediastinitis in one patient and tracheo-oesophageal fistulas in two patients. The mean duration of palliation before the development of recurrent dysphagia was 35 days. The mean survival was 82 days. Endoscopic alcohol injection is effective in relieving malignant dysphagia. This inexpensive and easily available technique merits comparative studies with more established forms of therapy, such as laser photocoagulation.

Original languageEnglish (US)
Pages (from-to)275-277
Number of pages3
JournalEndoscopy
Volume26
Issue number3
StatePublished - 1994
Externally publishedYes

Fingerprint

Deglutition Disorders
Alcohols
Injections
Esophageal Fistula
Mediastinitis
Cardia
Sclerotherapy
Light Coagulation
Esophageal Neoplasms
Stomach Neoplasms
Needles
Dilatation
Lasers
Ethanol
Therapeutics
Survival
Neoplasms

ASJC Scopus subject areas

  • Medicine (miscellaneous)

Cite this

Chung, S. C. S., Leong, H. T., Choi, C. Y. C., Leung, J., & Li, A. K. C. (1994). Palliation of malignant oesophageal obstruction by endoscopic alcohol injection. Endoscopy, 26(3), 275-277.

Palliation of malignant oesophageal obstruction by endoscopic alcohol injection. / Chung, S. C S; Leong, H. T.; Choi, C. Y C; Leung, Joseph; Li, A. K C.

In: Endoscopy, Vol. 26, No. 3, 1994, p. 275-277.

Research output: Contribution to journalArticle

Chung, SCS, Leong, HT, Choi, CYC, Leung, J & Li, AKC 1994, 'Palliation of malignant oesophageal obstruction by endoscopic alcohol injection', Endoscopy, vol. 26, no. 3, pp. 275-277.
Chung, S. C S ; Leong, H. T. ; Choi, C. Y C ; Leung, Joseph ; Li, A. K C. / Palliation of malignant oesophageal obstruction by endoscopic alcohol injection. In: Endoscopy. 1994 ; Vol. 26, No. 3. pp. 275-277.
@article{5118d51de59e408cb90ca8855f37363f,
title = "Palliation of malignant oesophageal obstruction by endoscopic alcohol injection",
abstract = "Thirty six-patients with inoperable cancers of the oesophagus or gastric tumour in the cardia were treated by endoscopic alcohol injection. After dilatation using Savary dilators, absolute alcohol was injected in 0.5-1 ml aliquots into protuberant parts using a sclerotherapy needle. The mean volume per session was 7.8 ml. The mean dysphagia score improved from 2.7 before treatment to 1.4 after treatment (p<0.001). Complications included mediastinitis in one patient and tracheo-oesophageal fistulas in two patients. The mean duration of palliation before the development of recurrent dysphagia was 35 days. The mean survival was 82 days. Endoscopic alcohol injection is effective in relieving malignant dysphagia. This inexpensive and easily available technique merits comparative studies with more established forms of therapy, such as laser photocoagulation.",
author = "Chung, {S. C S} and Leong, {H. T.} and Choi, {C. Y C} and Joseph Leung and Li, {A. K C}",
year = "1994",
language = "English (US)",
volume = "26",
pages = "275--277",
journal = "Endoscopy",
issn = "0013-726X",
publisher = "Georg Thieme Verlag",
number = "3",

}

TY - JOUR

T1 - Palliation of malignant oesophageal obstruction by endoscopic alcohol injection

AU - Chung, S. C S

AU - Leong, H. T.

AU - Choi, C. Y C

AU - Leung, Joseph

AU - Li, A. K C

PY - 1994

Y1 - 1994

N2 - Thirty six-patients with inoperable cancers of the oesophagus or gastric tumour in the cardia were treated by endoscopic alcohol injection. After dilatation using Savary dilators, absolute alcohol was injected in 0.5-1 ml aliquots into protuberant parts using a sclerotherapy needle. The mean volume per session was 7.8 ml. The mean dysphagia score improved from 2.7 before treatment to 1.4 after treatment (p<0.001). Complications included mediastinitis in one patient and tracheo-oesophageal fistulas in two patients. The mean duration of palliation before the development of recurrent dysphagia was 35 days. The mean survival was 82 days. Endoscopic alcohol injection is effective in relieving malignant dysphagia. This inexpensive and easily available technique merits comparative studies with more established forms of therapy, such as laser photocoagulation.

AB - Thirty six-patients with inoperable cancers of the oesophagus or gastric tumour in the cardia were treated by endoscopic alcohol injection. After dilatation using Savary dilators, absolute alcohol was injected in 0.5-1 ml aliquots into protuberant parts using a sclerotherapy needle. The mean volume per session was 7.8 ml. The mean dysphagia score improved from 2.7 before treatment to 1.4 after treatment (p<0.001). Complications included mediastinitis in one patient and tracheo-oesophageal fistulas in two patients. The mean duration of palliation before the development of recurrent dysphagia was 35 days. The mean survival was 82 days. Endoscopic alcohol injection is effective in relieving malignant dysphagia. This inexpensive and easily available technique merits comparative studies with more established forms of therapy, such as laser photocoagulation.

UR - http://www.scopus.com/inward/record.url?scp=0028324597&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028324597&partnerID=8YFLogxK

M3 - Article

C2 - 7521294

AN - SCOPUS:0028324597

VL - 26

SP - 275

EP - 277

JO - Endoscopy

JF - Endoscopy

SN - 0013-726X

IS - 3

ER -