Abstract
(Matrix presented) Palladium(0)-catalyzed cross-coupling reactions between tris(dihydropyranyl)indium 1 and aryl halides 2 have been investigated. Aryl iodides and electron-deficient aryl bromides couple efficiently with the in situ-generated indium reagents in the presence of 1-5 mol % Cl 2Pd(PPh3)2 to produce substituted dihydropyrans 3 with minimal (<10%) dimer (4) formation. Organoindium reagents derived from D-glucal also undergo cross couplings with aryl iodides to produce C-aryl glycals.
Original language | English (US) |
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Pages (from-to) | 2405-2408 |
Number of pages | 4 |
Journal | Organic Letters |
Volume | 5 |
Issue number | 14 |
DOIs | |
State | Published - Jul 10 2003 |
Externally published | Yes |
ASJC Scopus subject areas
- Molecular Medicine