Pain and functional outcomes of the sacroiliac joint after platelet-rich plasma injection: A descriptive review

Joshua B. Rothenberg, Keshav Godha, David M. Civitarese, Gerard Malanga, Jaspal Ricky Singh, Alberto Panero, Peter Everts, Marine DIdidze, Prathap Jayaram

Research output: Contribution to journalReview articlepeer-review

Abstract

The purpose of this manuscript is to highlight and review the status of literature regarding efficacy of platelet-rich plasma (PRP) in the treatment of sacroiliac joint (SIJ) dysfunction. A review of the literature on PRP interventions on the SIJ or ligaments was performed. Seven studies had improvements in their respective primary end point and demonstrated a strong safety profile without any serious adverse events. Only five articles demonstrated clinical efficacy of >50% in their primary outcome measures. There appears to be inconsistent and insufficient evidence for a conclusive recommendation for or against SIJ PRP. There is a need for adequately powered well-designed, standardized, double-blinded randomized clinical trials to determine the effectiveness of PRP in SIJ-mediated pain.

Original languageEnglish (US)
Pages (from-to)87-100
Number of pages14
JournalRegenerative Medicine
Volume16
Issue number1
DOIs
StatePublished - Jan 2021
Externally publishedYes

Keywords

  • bone and cartilage
  • chronic pain
  • hip pain
  • low back pain
  • musculoskeletal and joint disorders
  • orthopaedics
  • platelet-rich plasma
  • regenerative medicine
  • sacroiliac joint
  • sports medicine

ASJC Scopus subject areas

  • Biomedical Engineering
  • Embryology

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