Ozone and Oxygen Toxicity

Jerold A Last; D. M. Hyde; Edward S Schelegle

doi:10.1016/B978-0-08-046884-6.00913-1

Ozone and Oxygen Toxicity

Jerold A Last, D. M. Hyde, Edward S Schelegle

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Scopus citations

Abstract

Ozone is a ubiquitous air pollutant, especially in summer months due to the need for ultraviolet radiation for its atmospheric biosynthesis from its precursors, nitrogen oxides and volatile organic compounds. This chapter discusses the toxicological, epidemiological, and mechanistic evidence that concentrations of ozone at, or near, ambient levels are capable of causing acute and chronic lung injury and disease. The underlying cellular mechanisms of lung injury and repair are briefly discussed. Key studies that have informed Environmental Protection Agency's (EPA) risk assessment and standard setting are presented and analyzed.

Original language	English (US)
Title of host publication	Respiratory Toxicology
Publisher	Elsevier Inc.
Pages	261-275
Number of pages	15
Volume	8
ISBN (Print)	9780080468686
DOIs	https://doi.org/10.1016/B978-0-08-046884-6.00913-1
State	Published - Aug 12 2010

ASJC Scopus subject areas

Medicine(all)

Access to Document

10.1016/B978-0-08-046884-6.00913-1

Fingerprint Dive into the research topics of 'Ozone and Oxygen Toxicity'. Together they form a unique fingerprint.

Cite this

Last, J. A., Hyde, D. M., & Schelegle, E. S. (2010). Ozone and Oxygen Toxicity. In Respiratory Toxicology (Vol. 8, pp. 261-275). Elsevier Inc.. https://doi.org/10.1016/B978-0-08-046884-6.00913-1

@inbook{b6628a1cd75840718e0e255d6bd7981b,

title = "Ozone and Oxygen Toxicity",

abstract = "Ozone is a ubiquitous air pollutant, especially in summer months due to the need for ultraviolet radiation for its atmospheric biosynthesis from its precursors, nitrogen oxides and volatile organic compounds. This chapter discusses the toxicological, epidemiological, and mechanistic evidence that concentrations of ozone at, or near, ambient levels are capable of causing acute and chronic lung injury and disease. The underlying cellular mechanisms of lung injury and repair are briefly discussed. Key studies that have informed Environmental Protection Agency's (EPA) risk assessment and standard setting are presented and analyzed.",

author = "Last, {Jerold A} and Hyde, {D. M.} and Schelegle, {Edward S}",

year = "2010",

month = aug,

day = "12",

doi = "10.1016/B978-0-08-046884-6.00913-1",

language = "English (US)",

isbn = "9780080468686",

volume = "8",

pages = "261--275",

booktitle = "Respiratory Toxicology",

publisher = "Elsevier Inc.",

}

TY - CHAP

T1 - Ozone and Oxygen Toxicity

AU - Last, Jerold A

AU - Hyde, D. M.

AU - Schelegle, Edward S

PY - 2010/8/12

Y1 - 2010/8/12

N2 - Ozone is a ubiquitous air pollutant, especially in summer months due to the need for ultraviolet radiation for its atmospheric biosynthesis from its precursors, nitrogen oxides and volatile organic compounds. This chapter discusses the toxicological, epidemiological, and mechanistic evidence that concentrations of ozone at, or near, ambient levels are capable of causing acute and chronic lung injury and disease. The underlying cellular mechanisms of lung injury and repair are briefly discussed. Key studies that have informed Environmental Protection Agency's (EPA) risk assessment and standard setting are presented and analyzed.

AB - Ozone is a ubiquitous air pollutant, especially in summer months due to the need for ultraviolet radiation for its atmospheric biosynthesis from its precursors, nitrogen oxides and volatile organic compounds. This chapter discusses the toxicological, epidemiological, and mechanistic evidence that concentrations of ozone at, or near, ambient levels are capable of causing acute and chronic lung injury and disease. The underlying cellular mechanisms of lung injury and repair are briefly discussed. Key studies that have informed Environmental Protection Agency's (EPA) risk assessment and standard setting are presented and analyzed.

UR - http://www.scopus.com/inward/record.url?scp=85012836812&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85012836812&partnerID=8YFLogxK

U2 - 10.1016/B978-0-08-046884-6.00913-1

DO - 10.1016/B978-0-08-046884-6.00913-1

M3 - Chapter

AN - SCOPUS:85012836812

SN - 9780080468686

VL - 8

SP - 261

EP - 275

BT - Respiratory Toxicology

PB - Elsevier Inc.

ER -