Oxygen radicals and human disease. Davis conference

Carroll E Cross, B. Halliwell, E. T. Borish, W. A. Pryor, B. N. Ames, R. L. Saul, J. M. McCord, D. Harman

Research output: Contribution to journalArticle

1393 Citations (Scopus)

Abstract

Toxic oxygen free radicals have been implicated as important pathologic mediators in many clinical disorders. We discuss the chemistry of oxygen radical production and the roles of iron and of various antioxidants as well as the diseases that have received active attention in oxyradical research. Particular attention is focused on cigarette smoke oxidants, ischemia-reperfusion-induced radical production, carcinogenesis, and aging. Such research may well provide a firm foundation for therapeutic breakthroughs.

Original languageEnglish (US)
Pages (from-to)526-545
Number of pages20
JournalAnnals of Internal Medicine
Volume107
Issue number4
StatePublished - 1987

Fingerprint

Reactive Oxygen Species
Poisons
Research
Oxidants
Smoke
Tobacco Products
Reperfusion
Free Radicals
Carcinogenesis
Ischemia
Iron
Antioxidants
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Cross, C. E., Halliwell, B., Borish, E. T., Pryor, W. A., Ames, B. N., Saul, R. L., ... Harman, D. (1987). Oxygen radicals and human disease. Davis conference. Annals of Internal Medicine, 107(4), 526-545.

Oxygen radicals and human disease. Davis conference. / Cross, Carroll E; Halliwell, B.; Borish, E. T.; Pryor, W. A.; Ames, B. N.; Saul, R. L.; McCord, J. M.; Harman, D.

In: Annals of Internal Medicine, Vol. 107, No. 4, 1987, p. 526-545.

Research output: Contribution to journalArticle

Cross, CE, Halliwell, B, Borish, ET, Pryor, WA, Ames, BN, Saul, RL, McCord, JM & Harman, D 1987, 'Oxygen radicals and human disease. Davis conference', Annals of Internal Medicine, vol. 107, no. 4, pp. 526-545.
Cross CE, Halliwell B, Borish ET, Pryor WA, Ames BN, Saul RL et al. Oxygen radicals and human disease. Davis conference. Annals of Internal Medicine. 1987;107(4):526-545.
Cross, Carroll E ; Halliwell, B. ; Borish, E. T. ; Pryor, W. A. ; Ames, B. N. ; Saul, R. L. ; McCord, J. M. ; Harman, D. / Oxygen radicals and human disease. Davis conference. In: Annals of Internal Medicine. 1987 ; Vol. 107, No. 4. pp. 526-545.
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