Oxygen radicals and human disease. Davis conference

Carroll E Cross; B. Halliwell; E. T. Borish; W. A. Pryor; B. N. Ames; R. L. Saul; J. M. McCord; D. Harman

Oxygen radicals and human disease. Davis conference

Carroll E Cross, B. Halliwell, E. T. Borish, W. A. Pryor, B. N. Ames, R. L. Saul, J. M. McCord, D. Harman

Pulmonary, Critical Care, and Sleep Medicine

Research output: Contribution to journal › Article › peer-review

1445 Scopus citations

Abstract

Toxic oxygen free radicals have been implicated as important pathologic mediators in many clinical disorders. We discuss the chemistry of oxygen radical production and the roles of iron and of various antioxidants as well as the diseases that have received active attention in oxyradical research. Particular attention is focused on cigarette smoke oxidants, ischemia-reperfusion-induced radical production, carcinogenesis, and aging. Such research may well provide a firm foundation for therapeutic breakthroughs.

Original language	English (US)
Pages (from-to)	526-545
Number of pages	20
Journal	Annals of Internal Medicine
Volume	107
Issue number	4
State	Published - 1987

ASJC Scopus subject areas

Medicine(all)

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title = "Oxygen radicals and human disease. Davis conference",

abstract = "Toxic oxygen free radicals have been implicated as important pathologic mediators in many clinical disorders. We discuss the chemistry of oxygen radical production and the roles of iron and of various antioxidants as well as the diseases that have received active attention in oxyradical research. Particular attention is focused on cigarette smoke oxidants, ischemia-reperfusion-induced radical production, carcinogenesis, and aging. Such research may well provide a firm foundation for therapeutic breakthroughs.",

author = "Cross, {Carroll E} and B. Halliwell and Borish, {E. T.} and Pryor, {W. A.} and Ames, {B. N.} and Saul, {R. L.} and McCord, {J. M.} and D. Harman",

year = "1987",

language = "English (US)",

volume = "107",

pages = "526--545",

journal = "Annals of Internal Medicine",

issn = "0003-4819",

publisher = "American College of Physicians",

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T1 - Oxygen radicals and human disease. Davis conference

AU - Cross, Carroll E

AU - Halliwell, B.

AU - Borish, E. T.

AU - Pryor, W. A.

AU - Ames, B. N.

AU - Saul, R. L.

AU - McCord, J. M.

AU - Harman, D.

PY - 1987

Y1 - 1987

N2 - Toxic oxygen free radicals have been implicated as important pathologic mediators in many clinical disorders. We discuss the chemistry of oxygen radical production and the roles of iron and of various antioxidants as well as the diseases that have received active attention in oxyradical research. Particular attention is focused on cigarette smoke oxidants, ischemia-reperfusion-induced radical production, carcinogenesis, and aging. Such research may well provide a firm foundation for therapeutic breakthroughs.

AB - Toxic oxygen free radicals have been implicated as important pathologic mediators in many clinical disorders. We discuss the chemistry of oxygen radical production and the roles of iron and of various antioxidants as well as the diseases that have received active attention in oxyradical research. Particular attention is focused on cigarette smoke oxidants, ischemia-reperfusion-induced radical production, carcinogenesis, and aging. Such research may well provide a firm foundation for therapeutic breakthroughs.

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JO - Annals of Internal Medicine

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