Ovine pulmonary adenomatosis in Patagonia, Argentina

Francisco A Uzal, G. Delhon, P. R. Murcia, M. De las Heras, L. Luján, M. E. Fernández Miyakawa, W. E. Morris, M. J. Gonzalez

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


An outbreak of pulmonary adenomatosis (OPA) occurred in sheep in Patagonia, Argentina's southern-most region. On the affected farm, nine animals died over a 6-month period with pulmonary lesions of OPA. In all cases, the histology of the lungs was characterized by proliferation of cuboideal and prismatic cells lining the alveoli. Inflammatory exudates and accumulation of alveolar macrophages were marked in most cases, but in six of the cases there was no excess fluid in the airways. The presence of the Jaagsiekte retrovirus was demonstrated in the lungs by immunocytochemistry and PCR. To the best of our knowledge, this is the first report of OPA in Patagonia.

Original languageEnglish (US)
Pages (from-to)159-170
Number of pages12
JournalVeterinary Research Communications
Issue number2
StatePublished - Feb 2004


  • Adenomatosis
  • Immunocytochemistry
  • Jaagsiekte
  • Lung
  • PCR
  • Retrovirus
  • Sheep

ASJC Scopus subject areas

  • veterinary(all)


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