Overview of Antifungal Agents

George Richard Thompson, Jose Cadena, Thomas F. Patterson

Research output: Contribution to journalArticle

75 Scopus citations

Abstract

This article is a comprehensive clinically focused review of currently available antifungals administered by way of the intravenous or inhalational route: amphotericin B and its lipid formulations, fluconazole, itraconazole, posaconazole, voriconazole, caspofungin, micafungin, anidulafungin, and flucytosine. Emphasis is placed on pharmacodynamics and kinetics, drug interactions, adverse events, and evidence for their use. Selected clinical trials demonstrating the efficacy of these agents are also reviewed.

Original languageEnglish (US)
Pages (from-to)203-215
Number of pages13
JournalClinics in Chest Medicine
Volume30
Issue number2
DOIs
StatePublished - Jun 2009
Externally publishedYes

Keywords

  • Amphotericin
  • Echinocandins
  • Flucytosine
  • Fungal infection
  • Invasive mycoses
  • Triazoles

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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