Outcomes of dogs with grade 3 mast cell tumors: 43 cases (1997-2007)

Carrie Tupper Hume, Matti Kiupel, Lora Rigatti, Frances S. Shofer, Katherine A Skorupski, Karin U. Sorenmo

Research output: Contribution to journalArticlepeer-review

41 Scopus citations


This study reports the outcomes of dogs with grade 3 mast cell tumors (MCTs). Clinical and histopathological data were available for 43 dogs. Median progression-free survival (PFS) and overall survival (OS) were 133 and 257 days, respectively. Tumor size, lymph node (LN) status, and mitotic index (MI) significantly influenced PFS in univariate analysis. Tumor size and LN status remained significant in the multivariate analysis. Lymph node status, local tumor control, LN treatment, and MI significantly influenced OS in univariate analysis but only LN status remained significant in multivariate analysis. These results confirm that locoregional control improves outcomes in patients with grade 3 MCTs.

Original languageEnglish (US)
Pages (from-to)37-44
Number of pages8
JournalJournal of the American Animal Hospital Association
Issue number1
StatePublished - Jan 2011

ASJC Scopus subject areas

  • Small Animals


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