Outcome of 19 dogs with parathyroid carcinoma after surgical excision

E. S. Sawyer, N. C. Northrup, C. W. Schmiedt, William T Culp, K. M. Rassnick, L. D. Garrett, K. A. Selting, C. F. Saba, E. W. Howerth

Research output: Contribution to journalArticle

16 Scopus citations

Abstract

Parathyroid carcinoma (PTC) is rare in dogs and there is little information documenting its treatment and prognosis. The objective of this study was to describe the outcome of dogs with PTC treated with surgical excision. Medical records of 19 dogs undergoing surgical excision of PTC between 1990 and 2010 were reviewed retrospectively. Dogs were presented for clinical hypercalcaemia or incidental hypercalcaemia noted by referring veterinarians on routine serum chemistry profiles. A parathyroid nodule was identified with cervical ultrasound in 17/17 dogs. Hypercalcaemia resolved in 18/19 dogs within 4 days postoperatively. Nine developed hypocalcaemia. None were confirmed to develop recurrent or metastatic PTC. The only death associated with PTC was a dog that was euthanized for intractable hypocalcaemia 9 days after surgery. Estimated 1-, 2- and 3-year survival rates were 72, 37 and 30%, respectively. Excision of PTC results in resolution of hypercalcaemia and excellent tumour control.

Original languageEnglish (US)
Pages (from-to)57-64
Number of pages8
JournalVeterinary and Comparative Oncology
Volume10
Issue number1
DOIs
StatePublished - Mar 2012

Keywords

  • Canine
  • Endocrinology
  • Oncology

ASJC Scopus subject areas

  • veterinary(all)

Fingerprint Dive into the research topics of 'Outcome of 19 dogs with parathyroid carcinoma after surgical excision'. Together they form a unique fingerprint.

  • Cite this

    Sawyer, E. S., Northrup, N. C., Schmiedt, C. W., Culp, W. T., Rassnick, K. M., Garrett, L. D., Selting, K. A., Saba, C. F., & Howerth, E. W. (2012). Outcome of 19 dogs with parathyroid carcinoma after surgical excision. Veterinary and Comparative Oncology, 10(1), 57-64. https://doi.org/10.1111/j.1476-5829.2011.00276.x