Abstract
Background: It is essential to identify patients at high risk of death and complications for future studies of interventions to decrease reperfusion injury. Methods: We conducted an inception cohort study at a Level I trauma center to determine the rates and predictors of death, organ failure, and infection in trauma patients with systolic blood pressure ≤ 90 mm Hg in the field or in the emergency department. Results: Among the 208 patients with hemorrhagic shock (blood pressure ≤ 90 mm Hg), 31% died within 2 hours of emergency department arrival, 12% died between 2 and 24 hours, 11% died after 24 hours, and 46% survived. Among those who survived ≤ 24 hours, 39% developed infection and 24% developed organ failure. Increasing volume of crystalloid in the first 24 hours was strongly associated with increased mortality (p = 0.00001). Conclusion: Hemorrhage-induced hypotension in trauma patients is predictive of high mortality (54%) and morbidity. The requirement for large volumes of crystalloid was associated with increased mortality.
Original language | English (US) |
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Pages (from-to) | 545-549 |
Number of pages | 5 |
Journal | Journal of Trauma - Injury, Infection and Critical Care |
Volume | 45 |
Issue number | 3 |
DOIs | |
State | Published - Sep 1 1998 |
Externally published | Yes |
Keywords
- Cohort studies
- Injury Severity Score
- Mortality
- Multiple organ failure
- Risk factors
- Wounds and injuries
ASJC Scopus subject areas
- Surgery
- Critical Care and Intensive Care Medicine