Outbreaks of bovine herpesvirus 2 infections in calves causing ear and facial skin lesions

Tatiane T.Negrão Watanabe, Robert B. Moeller, Beate Crossley, Patricia C Blanchard

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

We describe 3 outbreaks of superficial dermatitis caused by bovine herpesvirus 2 (BoHV-2) in dairy breed calves. Clinically, all of the affected calves were 12–26 d of age, had alopecia and crusts on the face and ears, and were non-pruritic and afebrile. Affected animals recovered spontaneously without any treatment within 2–4 wk after onset of clinical signs based on 1 herd with follow up. Histologic examination of all skin crust or tissue samples identified neutrophilic inflammation, mild hyperkeratosis, multinucleate syncytial cells, and intranuclear inclusion bodies in the syncytial cells. Real-time PCR testing on affected surface crusts or tissue provided evidence of BoHV-2, and testing, where performed, was negative for parapoxvirus including bovine papular stomatitis virus and the ovine form of malignant catarrhal fever tested in EDTA blood samples. Bovine viral diarrhea virus also was negative by ELISA, as well as bovine herpesvirus 1 by immunohistochemistry. Direct electron microscopy of infected tissues in the first outbreak revealed herpesvirus-like particles.

Original languageEnglish (US)
Pages (from-to)686-690
Number of pages5
JournalJournal of Veterinary Diagnostic Investigation
Volume29
Issue number5
DOIs
StatePublished - Sep 1 2017

Fingerprint

Bovine Herpesvirus 2
Bovine herpesvirus 2
Herpesviridae Infections
skin lesions
Disease Outbreaks
Ear
ears
calves
Malignant Catarrh
Skin
Bovine papular stomatitis virus
Parapoxvirus
nuclear inclusions
infection
Bovine Herpesvirus 1
Bovine Viral Diarrhea Viruses
malignant catarrhal fever
Intranuclear Inclusion Bodies
hyperkeratosis
dairy breeds

Keywords

  • Bovine herpesvirus 2
  • bovine mammillitis virus
  • calves
  • polymerase chain reaction
  • pseudo-lumpy skin disease

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Outbreaks of bovine herpesvirus 2 infections in calves causing ear and facial skin lesions. / Watanabe, Tatiane T.Negrão; Moeller, Robert B.; Crossley, Beate; Blanchard, Patricia C.

In: Journal of Veterinary Diagnostic Investigation, Vol. 29, No. 5, 01.09.2017, p. 686-690.

Research output: Contribution to journalArticle

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