TY - JOUR
T1 - Otomycosis due to coccidioidomycosis
AU - Harvey, R. P.
AU - Pappagianis, Demosthenes
AU - Cochran, J.
AU - Stevens, D. A.
PY - 1978
Y1 - 1978
N2 - The course and treatment of two patients with otomycosis due to Coccidioides immitis, believed to be the first such cases reported, are described. Both infections appeared due to reactivation of hematogenously disseminated foci. Local and systemic chemotherapy plus surgery resulted in remission, and host immune response also appears to be an important factor. One patient, with systemic lupus erythematosus, required more extensive surgery, more chemotherapy, and reduction in steroid dose to arrest the disease. A combined surgical and chemotherapeutic approach appears necessary when otomycosis is due to invasive fungi such as C. immitis.
AB - The course and treatment of two patients with otomycosis due to Coccidioides immitis, believed to be the first such cases reported, are described. Both infections appeared due to reactivation of hematogenously disseminated foci. Local and systemic chemotherapy plus surgery resulted in remission, and host immune response also appears to be an important factor. One patient, with systemic lupus erythematosus, required more extensive surgery, more chemotherapy, and reduction in steroid dose to arrest the disease. A combined surgical and chemotherapeutic approach appears necessary when otomycosis is due to invasive fungi such as C. immitis.
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U2 - 10.1001/archinte.138.9.1434
DO - 10.1001/archinte.138.9.1434
M3 - Article
C2 - 686941
AN - SCOPUS:0018202769
VL - 138
SP - 1434
EP - 1435
JO - JAMA Internal Medicine
JF - JAMA Internal Medicine
SN - 2168-6106
IS - 9
ER -