Osteoporosis in the rheumatic disease patient

Nancy E Lane, Q. Rehman

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


Rheumatic disease patients often have both systemic and localized inflammatory processes. The result of this inflammation is tissue destruction and this translates into bone loss. Recent studies have highlighted the importance of systemic factors that either directly or indirectly activate receptor activator of nuclear factor-kB ligand (RANKL) dependent osteoclast activation and induce bone loss. In this article we will review the pathogenesis of inflammatory bone loss and explore the possible interventions to prevent it.

Original languageEnglish (US)
Pages (from-to)675-679
Number of pages5
Issue number10
StatePublished - 2002
Externally publishedYes


  • Bone loss
  • Rheumatology patients

ASJC Scopus subject areas

  • Rheumatology
  • Immunology


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