Abstract
Rheumatic disease patients often have both systemic and localized inflammatory processes. The result of this inflammation is tissue destruction and this translates into bone loss. Recent studies have highlighted the importance of systemic factors that either directly or indirectly activate receptor activator of nuclear factor-kB ligand (RANKL) dependent osteoclast activation and induce bone loss. In this article we will review the pathogenesis of inflammatory bone loss and explore the possible interventions to prevent it.
Original language | English (US) |
---|---|
Pages (from-to) | 675-679 |
Number of pages | 5 |
Journal | Lupus |
Volume | 11 |
Issue number | 10 |
DOIs | |
State | Published - 2002 |
Externally published | Yes |
Keywords
- Bone loss
- Rheumatology patients
ASJC Scopus subject areas
- Rheumatology
- Immunology