Osteoporosis and systemic lupus erythematosus: Etiology and treatment strategies

Leigh G. Segal, Nancy E Lane

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


The importance of bone loss in patients with systemic lupus erythematosus can not be over emphasized. Risk factors for osteoporosis in these patients include not only those that apply to the general population, but also many that are related to the underlying disease process, or its treatment. Ongoing research should attempt to clarify the prevalence of low bone mass in lupus, as well as the pathogenic mechanisms applying especially to this population. Strategies for the prevention and treatment of bone loss in lupus patients do not differ significantly from those in the general population. Special attention must be given to the prevention of steroid-induced bone loss, as well as to the gonadal effects of cytotoxic agents.

Original languageEnglish (US)
Pages (from-to)281-289
Number of pages9
JournalAnnales de Medecine Interne
Issue number4
StatePublished - 1996
Externally publishedYes


  • lupus
  • osteoporosis
  • prevention
  • treatment

ASJC Scopus subject areas

  • Internal Medicine
  • Medicine(all)


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