Osseointegration of Coarse and Fine Textured Implants Manufactured by Electron Beam Melting and Direct Metal Laser Sintering

David S. Ruppert, Ola L.A. Harrysson, Denis J Marcellin-Little, Sam Abumoussa, Laurence E. Dahners, Paul S. Weinhold

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

Osseointegrated implants transfer loads from native bone to a synthetic joint and can also function transdermally to provide a stable connection between the skeleton and the prostheses, eliminating many problems associated with socket prostheses. Additive manufacturing provides a cost-effective means to create patient-specific implants and allows for customized textures for integration with bone and other tissues. Our objective was to compare the osseointegration strength of two primary additive manufacturing methods of producing textured implants: electron beam melting (EBM) (mean Ra = 23 μm) and direct metal laser sintering (DMLS) (mean Ra = 10 μm). Due to spatial resolution, DMLS can produce surfaces with a roughness comparable to EBM. Two cohorts of Sprague-Dawley rats received bilateral, titanium implants in their distal femurs and were followed for 4 weeks. The first-cohort animals received EBM implants transcortically in one femur and a DMLS implant in the contralateral femur. The second cohort received DMLS implants (either fine textured or coarse textured to mimic EBM) in the intramedullary canal of each femur. Osseointegration was evaluated through mechanical testing and micro-computed tomography (bone volume fraction [BV/TV] and bone-implant contact [BIC]). The fixation strength of coarse textured implants provided superior interlocking relative to fine textured implants without affecting BV/TV or BIC in both cohorts. Coarse EBM implants in a transcortical model demonstrated an 85% increase in removal torque relative to the fine DMLS textured implants. The thrust load in the intramedullary model saw a 35% increase from fine to coarse DMLS implants.

Original languageEnglish (US)
Pages (from-to)91-97
Number of pages7
Journal3D Printing and Additive Manufacturing
Volume4
Issue number2
DOIs
StatePublished - Jun 1 2017
Externally publishedYes

Keywords

  • additive manufactured implants
  • bone-implant interface
  • direct metal laser sintering
  • electron beam melting
  • osseointegration of transcutaneous prostheses

ASJC Scopus subject areas

  • Industrial and Manufacturing Engineering
  • Materials Science (miscellaneous)

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