Orthodromic and antidromic effects of a cortical epileptiform focus on ventrolateral nucleus of the cat

Philip A Schwartzkroin, R. Mutani, D. A. Prince

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Abstract

The VL unit population studied during the experiments was similar in its normal patterns of activation (BC and antidromically evoked) to that described by several other workers. The authors were not able to distinguish between relay cells and interneurons on the basis of the neuronal response to BC stimulation; neither latency nor number of spikes in the response seemed to distinguish those cells antidromically activated by cortical stimulation (40 to 45%) from those that were not. Cortical orthodromic activation of VL cells at short latency (3 to 4 min), as reported by others was not usually observed in the preparation. Recruitment of the short latency response may require more rapid repetitive stimulation than was normally delivered, or more careful 'on line' placement of stimulating and recording electrodes.

Original languageEnglish (US)
Pages (from-to)795-811
Number of pages17
JournalJournal of Neurophysiology
Volume38
Issue number4
StatePublished - 1975
Externally publishedYes

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ASJC Scopus subject areas

  • Physiology
  • Neuroscience(all)

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