ORIGINAL RESEARCH: The effects of body weight, body condition score, sex, and age on serum fructosamine concentrations in clinically healthy cats

Chen Gilor, Thomas K. Graves, B. Duncan X Lascelles, Andrea E. Thomson, Wendy Simpson, David S. Halpern

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Serum fructosamine (SF) concentrations depend on plasma glucose concentrations and are used to evaluate glycemic control in animals with diabetes mellitus (DM). Despite the strong association between obesity and DM, the effects of body weight (BW) and body condition on SF concentrations in clinically healthy cats have not been reported.Objective: The aim of the study was to evaluate the effects of BW, body condition score (BCS), sex, and age on SF concentrations in healthy cats.Methods: BW, BCS, and SF concentrations were determined in 84 clinically healthy client-owned cats (50 neutered males, 33 spayed females, and 1 intact female) of known age. The cats were enrolled prospectively in the study.Results: Mean BW, median BCS, and mean SF concentrations for the 84 cats were 5.4 kg, 5/9, and 268.7±45.5 μmol/L (range 197-399), respectively. BW was weakly but significantly correlated with SF (r=.26; P=.02), whereas BCS was not. Cats weighing >5.4 kg and cats with BCS>5/9 had higher mean SF concentrations compared with cats weighing <5.4 kg and cats with BCS <5/9, respectively. Cats categorized as normal weight to obese by BW (BW≥4.0 kg) had higher mean SF concentrations compared with cats categorized as lean (BW<4.0 kg). For domestic shorthair cats, the same was true for BCS: cats with BCS≥4/9 had higher mean fructosamine concentrations than those with BCS<4/9. Male cats had significantly higher mean SF concentrations compared with female cats (285.1±45.3 vs 244.5±33.9 μmol/L, P<.001). Age did not affect mean SF concentrations.Conclusions: BW is positively correlated with SF concentration, and lean cats have lower SF concentrations than normal and obese cats. In contrast to previous reports, mean SF concentrations were higher in male cats than in female cats, even when males and females were matched based on BW, BCS, and age.

Original languageEnglish (US)
Pages (from-to)322-328
Number of pages7
JournalVeterinary Clinical Pathology
Volume39
Issue number3
DOIs
StatePublished - Sep 2010
Externally publishedYes

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Fructosamine
body condition
Cats
Body Weight
cats
body weight
gender
Serum
diabetes mellitus
Diabetes Mellitus

Keywords

  • Diabetes mellitus
  • Feline
  • Glycemic control
  • Obesity

ASJC Scopus subject areas

  • veterinary(all)

Cite this

ORIGINAL RESEARCH : The effects of body weight, body condition score, sex, and age on serum fructosamine concentrations in clinically healthy cats. / Gilor, Chen; Graves, Thomas K.; Lascelles, B. Duncan X; Thomson, Andrea E.; Simpson, Wendy; Halpern, David S.

In: Veterinary Clinical Pathology, Vol. 39, No. 3, 09.2010, p. 322-328.

Research output: Contribution to journalArticle

Gilor, Chen ; Graves, Thomas K. ; Lascelles, B. Duncan X ; Thomson, Andrea E. ; Simpson, Wendy ; Halpern, David S. / ORIGINAL RESEARCH : The effects of body weight, body condition score, sex, and age on serum fructosamine concentrations in clinically healthy cats. In: Veterinary Clinical Pathology. 2010 ; Vol. 39, No. 3. pp. 322-328.
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AU - Thomson, Andrea E.

AU - Simpson, Wendy

AU - Halpern, David S.

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N2 - Serum fructosamine (SF) concentrations depend on plasma glucose concentrations and are used to evaluate glycemic control in animals with diabetes mellitus (DM). Despite the strong association between obesity and DM, the effects of body weight (BW) and body condition on SF concentrations in clinically healthy cats have not been reported.Objective: The aim of the study was to evaluate the effects of BW, body condition score (BCS), sex, and age on SF concentrations in healthy cats.Methods: BW, BCS, and SF concentrations were determined in 84 clinically healthy client-owned cats (50 neutered males, 33 spayed females, and 1 intact female) of known age. The cats were enrolled prospectively in the study.Results: Mean BW, median BCS, and mean SF concentrations for the 84 cats were 5.4 kg, 5/9, and 268.7±45.5 μmol/L (range 197-399), respectively. BW was weakly but significantly correlated with SF (r=.26; P=.02), whereas BCS was not. Cats weighing >5.4 kg and cats with BCS>5/9 had higher mean SF concentrations compared with cats weighing <5.4 kg and cats with BCS <5/9, respectively. Cats categorized as normal weight to obese by BW (BW≥4.0 kg) had higher mean SF concentrations compared with cats categorized as lean (BW<4.0 kg). For domestic shorthair cats, the same was true for BCS: cats with BCS≥4/9 had higher mean fructosamine concentrations than those with BCS<4/9. Male cats had significantly higher mean SF concentrations compared with female cats (285.1±45.3 vs 244.5±33.9 μmol/L, P<.001). Age did not affect mean SF concentrations.Conclusions: BW is positively correlated with SF concentration, and lean cats have lower SF concentrations than normal and obese cats. In contrast to previous reports, mean SF concentrations were higher in male cats than in female cats, even when males and females were matched based on BW, BCS, and age.

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