TY - JOUR

T1 - Ordinary versus random-effects logistic regression for analyzing herd-level calf morbidity and mortality data

AU - Curtis, Charles R.

AU - Mauritsen, Robert H.

AU - Kass, Philip H

AU - Salman, Mowafak D.

AU - Erb, Hollis N.

PY - 1993

Y1 - 1993

N2 - The analysis of data from populations organized into groups is frequently complicated by cluster (herd) effects. When present, clustering effects influence the probability of a health-related event in a way that is not readily accounted for with classical fixed-effects models (including unconditional logistic regression). Clustering introduces an additional source of (extra-binomial) variation into a logistic regression model, violating the independence and identical-distribution assumptions, and leading to biased variance estimators and spurious statistical significance. One remedy is to treat herd effects as random effects, so that variation even from unmeasured and unmeasurable (but clustered) sources can be accounted for. The logistic-normal regression model is introduced as one such random-effects model; its application is demonstrated using data from a previously described study of calfhood morbidity and mortality in 25 New York dairy herds.

AB - The analysis of data from populations organized into groups is frequently complicated by cluster (herd) effects. When present, clustering effects influence the probability of a health-related event in a way that is not readily accounted for with classical fixed-effects models (including unconditional logistic regression). Clustering introduces an additional source of (extra-binomial) variation into a logistic regression model, violating the independence and identical-distribution assumptions, and leading to biased variance estimators and spurious statistical significance. One remedy is to treat herd effects as random effects, so that variation even from unmeasured and unmeasurable (but clustered) sources can be accounted for. The logistic-normal regression model is introduced as one such random-effects model; its application is demonstrated using data from a previously described study of calfhood morbidity and mortality in 25 New York dairy herds.

UR - http://www.scopus.com/inward/record.url?scp=38249001505&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=38249001505&partnerID=8YFLogxK

U2 - 10.1016/0167-5877(93)90067-4

DO - 10.1016/0167-5877(93)90067-4

M3 - Article

AN - SCOPUS:38249001505

VL - 16

SP - 207

EP - 222

JO - Preventive Veterinary Medicine

JF - Preventive Veterinary Medicine

SN - 0167-5877

IS - 3

ER -