Ordering in bio-inorganic hybrid nanomaterials probed by in situ scanning transmission X-ray microscopy

Jonathan R I Lee, Michael Bagge-Hansen, Ramya Tunuguntla, Kyunghoon Kim, Mangesh Bangar, Trevor M. Willey, Ich C. Tran, David A. Kilcoyne, Aleksandr Noy, Tony Van Buuren

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Phospholipid bilayer coated Si nanowires are one-dimensional (1D) composites that provide versatile bio-nanoelectronic functionality via incorporation of a wide variety of biomolecules into the phospholipid matrix. The physiochemical behaviour of the phospholipid bilayer is strongly dependent on its structure and, as a consequence, substantial modelling and experimental efforts have been directed at the structural characterization of supported bilayers and unsupported phospholipid vesicles; nonetheless, the experimental studies conducted to date have exclusively involved volume-averaged techniques, which do not allow for the assignment of spatially resolved structural variations that could critically impact the performance of the 1D phospholipid-Si NW composites. In this manuscript, we use scanning transmission X-ray microscopy (STXM) to probe bond orientation and bilayer thickness as a function of position with a spatial resolution of ∼30 nm for Δ9-cis 1,2-dioleoyl-sn-glycero-3-phosphocholine layers prepared Si NWs. When coupled with small angle X-ray scattering measurements, the STXM data reveal structural motifs of the Si NWs that give rise to multi-bilayer formation and enable assignment of the orientation of specific bonds known to affect the order and rigidity of phospholipid bilayers.

Original languageEnglish (US)
Pages (from-to)9477-9486
Number of pages10
JournalNanoscale
Volume7
Issue number21
DOIs
StatePublished - Jun 7 2015
Externally publishedYes

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Phospholipids
Nanostructured materials
Microscopic examination
Scanning
X rays
Nanoelectronics
Composite materials
Biomolecules
X ray scattering
Rigidity
Nanowires

ASJC Scopus subject areas

  • Materials Science(all)

Cite this

Lee, J. R. I., Bagge-Hansen, M., Tunuguntla, R., Kim, K., Bangar, M., Willey, T. M., ... Van Buuren, T. (2015). Ordering in bio-inorganic hybrid nanomaterials probed by in situ scanning transmission X-ray microscopy. Nanoscale, 7(21), 9477-9486. https://doi.org/10.1039/c5nr00622h

Ordering in bio-inorganic hybrid nanomaterials probed by in situ scanning transmission X-ray microscopy. / Lee, Jonathan R I; Bagge-Hansen, Michael; Tunuguntla, Ramya; Kim, Kyunghoon; Bangar, Mangesh; Willey, Trevor M.; Tran, Ich C.; Kilcoyne, David A.; Noy, Aleksandr; Van Buuren, Tony.

In: Nanoscale, Vol. 7, No. 21, 07.06.2015, p. 9477-9486.

Research output: Contribution to journalArticle

Lee, JRI, Bagge-Hansen, M, Tunuguntla, R, Kim, K, Bangar, M, Willey, TM, Tran, IC, Kilcoyne, DA, Noy, A & Van Buuren, T 2015, 'Ordering in bio-inorganic hybrid nanomaterials probed by in situ scanning transmission X-ray microscopy', Nanoscale, vol. 7, no. 21, pp. 9477-9486. https://doi.org/10.1039/c5nr00622h
Lee JRI, Bagge-Hansen M, Tunuguntla R, Kim K, Bangar M, Willey TM et al. Ordering in bio-inorganic hybrid nanomaterials probed by in situ scanning transmission X-ray microscopy. Nanoscale. 2015 Jun 7;7(21):9477-9486. https://doi.org/10.1039/c5nr00622h
Lee, Jonathan R I ; Bagge-Hansen, Michael ; Tunuguntla, Ramya ; Kim, Kyunghoon ; Bangar, Mangesh ; Willey, Trevor M. ; Tran, Ich C. ; Kilcoyne, David A. ; Noy, Aleksandr ; Van Buuren, Tony. / Ordering in bio-inorganic hybrid nanomaterials probed by in situ scanning transmission X-ray microscopy. In: Nanoscale. 2015 ; Vol. 7, No. 21. pp. 9477-9486.
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