Oral medications for treating diabetes mellitus in dogs and cats

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Five classes of oral hypoglycaemic drugs and two trace minerals used to treat diabetes mellitus in humans are reviewed and current knowledge on the use of these drugs in diabetic dogs and cats is presented. Oral sulphonylurea drugs stimulate insulin secretion and have been used successfully to treat diabetes in cats but not dogs. Preliminary studies evaluating the efficacy of the biguanide, metformin, in diabetic cats have not been promising. Pharmacokinetic studies have been performed in healthy cats, but clinical studies evaluating the efficacy of the insulin-sensitising drugs, thiazolidinediones, have not been reported. Treatment with the alpha-glucosidase inhibitor, acarbose, improved control of glycaemia in diabetic dogs; similar studies have not been reported in cats. Although chromium picolinate did not improve control of glycaemia in diabetic dogs, vanadium has improved control of the abnormality in diabetic cats.

Original languageEnglish (US)
Pages (from-to)486-490
Number of pages5
JournalJournal of Small Animal Practice
Volume41
Issue number11
StatePublished - Nov 2000

Fingerprint

diabetes mellitus
drug therapy
mouth
Diabetes Mellitus
Cats
Dogs
cats
dogs
drugs
blood glucose
biguanides
acarbose
Pharmaceutical Preparations
Insulin
Acarbose
hypoglycemic agents
metformin
Biguanides
sulfonylureas
Thiazolidinediones

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Oral medications for treating diabetes mellitus in dogs and cats. / Nelson, Richard W.

In: Journal of Small Animal Practice, Vol. 41, No. 11, 11.2000, p. 486-490.

Research output: Contribution to journalArticle

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