Oral findings in fragile X syndrome

W. C. Shellhart, P. S. Casamassimo, Randi J Hagerman, G. K. Belanger

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


This study compares the oral findings in fragile X syndrome individuals to those of normal age-matched patients. Sixteen fra(X) males (mean age 22 10/12 years) had a low caries rate (decayed, missing and filled surfaces (DMFS) = 12.3) and minimal intraoral hard or soft tissue disease. Rate of malocclusion, as determined by the first permanent molar classification of Angle, was not significantly different from that of matched subjects. Fra(X) subjects had a significantly higher occurrence of malocclusion as compared to matched subjects using crossbite and openbite as criteria. Palatal dimensions of fra(X) subjects did not differ significantly from those of the matched sample. The fra(X) males also demonstrated significantly more severe occlusal wear of their teeth than the matched sample.

Original languageEnglish (US)
Pages (from-to)179-187
Number of pages9
JournalAmerican Journal of Medical Genetics
Issue number1-2
StatePublished - 1986
Externally publishedYes

ASJC Scopus subject areas

  • Genetics(clinical)


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