Glycogen was first identified in muscle almost 150 years ago. Even with this long history, the ability of glycogen to modulate metabolic signalling within muscle was not postulated until the discovery of glycogen binding domains suggested that glycogen could directly affect metabolic signalling within cells. Acute exercise induces a variety of metabolic signals including the AMP-activated protein kinase (AMPK), p38 MAPK, and protein kinase A (PKA). All of these signalling processes are also affected by glycogen depletion. This review will discuss the effect of exercise and glycogen depletion on these processes and how they potentially could affect the adaptation to exercise.
|Original language||English (US)|
|Number of pages||5|
|Journal||Agro Food Industry Hi-Tech|
|State||Published - Mar 2008|
ASJC Scopus subject areas
- Food Science