Optimising training adaptations by manipulating glycogen

Andrew Philp, Keith Baar

Research output: Contribution to journalArticle

Abstract

Glycogen was first identified in muscle almost 150 years ago. Even with this long history, the ability of glycogen to modulate metabolic signalling within muscle was not postulated until the discovery of glycogen binding domains suggested that glycogen could directly affect metabolic signalling within cells. Acute exercise induces a variety of metabolic signals including the AMP-activated protein kinase (AMPK), p38 MAPK, and protein kinase A (PKA). All of these signalling processes are also affected by glycogen depletion. This review will discuss the effect of exercise and glycogen depletion on these processes and how they potentially could affect the adaptation to exercise.

Original languageEnglish (US)
Pages (from-to)14-18
Number of pages5
JournalAgro Food Industry Hi-Tech
Volume19
Issue number2
StatePublished - Mar 2008
Externally publishedYes

ASJC Scopus subject areas

  • Food Science

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