Optimal Cutoff Scores for Alzheimer's Disease Using the Chinese Version of Mini-Mental State Examination among Chinese Population Living in Rural Areas

Zhao Yang; Hunter K. Holt; Jin Hu Fan; Li Ma; Ying Liu; Wen Chen; Peter Como; Lin Zhang; You Lin Qiao

doi:10.1177/1533317516662336

Optimal Cutoff Scores for Alzheimer's Disease Using the Chinese Version of Mini-Mental State Examination among Chinese Population Living in Rural Areas

Zhao Yang, Hunter K. Holt, Jin Hu Fan, Li Ma, Ying Liu, Wen Chen, Peter Como, Lin Zhang, You Lin Qiao

Neurology

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

To explore the optimal cutoff score for initial detection of Alzheimer's Disease (AD) through the Chinese version of Mini-Mental State Examination (CMMSE) in rural areas in China, we conducted a cross-sectional study within the Linxian General Population Nutritional Follow-up study. 16,488 eligible cohort members participated in the survey and 881 completed the CMMSE. Among 881 participants, the median age (Interquartile range) was 69.00 (10.00), 634 (71.92%) were female, 657 (74.57%) were illiterate, 35 (3.97%) had 6 years of education or higher, and 295 (33.48%) were diagnosed with AD. By reducing the CMMSE criteria for illiterate to 16 points, primary school to 19 points, and middle school or higher to 23 points, the efficiency of Chinese version of Mini-Mental State Examination can be significantly improved for initial detection of AD in rural areas in China, especially in those nutrition deficient areas.

Original language	English (US)
Pages (from-to)	650-657
Number of pages	8
Journal	American Journal of Alzheimer's Disease and other Dementias
Volume	31
Issue number	8
DOIs	https://doi.org/10.1177/1533317516662336
State	Published - Dec 1 2016

Keywords

Alzheimer's disease
Chinese population
Chinese version Mini-Mental State Examination
cutoff scores
ROC analysis
rural areas

ASJC Scopus subject areas

Clinical Psychology
Geriatrics and Gerontology
Psychiatry and Mental health

Access to Document

10.1177/1533317516662336

Fingerprint Dive into the research topics of 'Optimal Cutoff Scores for Alzheimer's Disease Using the Chinese Version of Mini-Mental State Examination among Chinese Population Living in Rural Areas'. Together they form a unique fingerprint.

Cite this

Yang, Z., Holt, H. K., Fan, J. H., Ma, L., Liu, Y., Chen, W., Como, P., Zhang, L., & Qiao, Y. L. (2016). Optimal Cutoff Scores for Alzheimer's Disease Using the Chinese Version of Mini-Mental State Examination among Chinese Population Living in Rural Areas. American Journal of Alzheimer's Disease and other Dementias, 31(8), 650-657. https://doi.org/10.1177/1533317516662336

Optimal Cutoff Scores for Alzheimer's Disease Using the Chinese Version of Mini-Mental State Examination among Chinese Population Living in Rural Areas. / Yang, Zhao; Holt, Hunter K.; Fan, Jin Hu; Ma, Li; Liu, Ying; Chen, Wen; Como, Peter; Zhang, Lin; Qiao, You Lin.

In: American Journal of Alzheimer's Disease and other Dementias, Vol. 31, No. 8, 01.12.2016, p. 650-657.

Research output: Contribution to journal › Article › peer-review

Yang, Z, Holt, HK, Fan, JH, Ma, L, Liu, Y, Chen, W, Como, P, Zhang, L & Qiao, YL 2016, 'Optimal Cutoff Scores for Alzheimer's Disease Using the Chinese Version of Mini-Mental State Examination among Chinese Population Living in Rural Areas', American Journal of Alzheimer's Disease and other Dementias, vol. 31, no. 8, pp. 650-657. https://doi.org/10.1177/1533317516662336

Yang, Zhao ; Holt, Hunter K. ; Fan, Jin Hu ; Ma, Li ; Liu, Ying ; Chen, Wen ; Como, Peter ; Zhang, Lin ; Qiao, You Lin. / Optimal Cutoff Scores for Alzheimer's Disease Using the Chinese Version of Mini-Mental State Examination among Chinese Population Living in Rural Areas. In: American Journal of Alzheimer's Disease and other Dementias. 2016 ; Vol. 31, No. 8. pp. 650-657.

@article{c98d7b314b6b475da48e844c8997483b,

title = "Optimal Cutoff Scores for Alzheimer's Disease Using the Chinese Version of Mini-Mental State Examination among Chinese Population Living in Rural Areas",

abstract = "To explore the optimal cutoff score for initial detection of Alzheimer's Disease (AD) through the Chinese version of Mini-Mental State Examination (CMMSE) in rural areas in China, we conducted a cross-sectional study within the Linxian General Population Nutritional Follow-up study. 16,488 eligible cohort members participated in the survey and 881 completed the CMMSE. Among 881 participants, the median age (Interquartile range) was 69.00 (10.00), 634 (71.92%) were female, 657 (74.57%) were illiterate, 35 (3.97%) had 6 years of education or higher, and 295 (33.48%) were diagnosed with AD. By reducing the CMMSE criteria for illiterate to 16 points, primary school to 19 points, and middle school or higher to 23 points, the efficiency of Chinese version of Mini-Mental State Examination can be significantly improved for initial detection of AD in rural areas in China, especially in those nutrition deficient areas.",

keywords = "Alzheimer's disease, Chinese population, Chinese version Mini-Mental State Examination, cutoff scores, ROC analysis, rural areas",

author = "Zhao Yang and Holt, {Hunter K.} and Fan, {Jin Hu} and Li Ma and Ying Liu and Wen Chen and Peter Como and Lin Zhang and Qiao, {You Lin}",

year = "2016",

month = dec,

day = "1",

doi = "10.1177/1533317516662336",

language = "English (US)",

volume = "31",

pages = "650--657",

journal = "American Journal of Alzheimer's Disease and other Dementias",

issn = "1533-3175",

publisher = "SAGE Publications Inc.",

number = "8",

}

TY - JOUR

T1 - Optimal Cutoff Scores for Alzheimer's Disease Using the Chinese Version of Mini-Mental State Examination among Chinese Population Living in Rural Areas

AU - Yang, Zhao

AU - Holt, Hunter K.

AU - Fan, Jin Hu

AU - Ma, Li

AU - Liu, Ying

AU - Chen, Wen

AU - Como, Peter

AU - Zhang, Lin

AU - Qiao, You Lin

PY - 2016/12/1

Y1 - 2016/12/1

N2 - To explore the optimal cutoff score for initial detection of Alzheimer's Disease (AD) through the Chinese version of Mini-Mental State Examination (CMMSE) in rural areas in China, we conducted a cross-sectional study within the Linxian General Population Nutritional Follow-up study. 16,488 eligible cohort members participated in the survey and 881 completed the CMMSE. Among 881 participants, the median age (Interquartile range) was 69.00 (10.00), 634 (71.92%) were female, 657 (74.57%) were illiterate, 35 (3.97%) had 6 years of education or higher, and 295 (33.48%) were diagnosed with AD. By reducing the CMMSE criteria for illiterate to 16 points, primary school to 19 points, and middle school or higher to 23 points, the efficiency of Chinese version of Mini-Mental State Examination can be significantly improved for initial detection of AD in rural areas in China, especially in those nutrition deficient areas.

AB - To explore the optimal cutoff score for initial detection of Alzheimer's Disease (AD) through the Chinese version of Mini-Mental State Examination (CMMSE) in rural areas in China, we conducted a cross-sectional study within the Linxian General Population Nutritional Follow-up study. 16,488 eligible cohort members participated in the survey and 881 completed the CMMSE. Among 881 participants, the median age (Interquartile range) was 69.00 (10.00), 634 (71.92%) were female, 657 (74.57%) were illiterate, 35 (3.97%) had 6 years of education or higher, and 295 (33.48%) were diagnosed with AD. By reducing the CMMSE criteria for illiterate to 16 points, primary school to 19 points, and middle school or higher to 23 points, the efficiency of Chinese version of Mini-Mental State Examination can be significantly improved for initial detection of AD in rural areas in China, especially in those nutrition deficient areas.

KW - Alzheimer's disease

KW - Chinese population

KW - Chinese version Mini-Mental State Examination

KW - cutoff scores

KW - ROC analysis

KW - rural areas

UR - http://www.scopus.com/inward/record.url?scp=84994318950&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84994318950&partnerID=8YFLogxK

U2 - 10.1177/1533317516662336

DO - 10.1177/1533317516662336

M3 - Article

C2 - 27659393

AN - SCOPUS:84994318950

VL - 31

SP - 650

EP - 657

JO - American Journal of Alzheimer's Disease and other Dementias

JF - American Journal of Alzheimer's Disease and other Dementias

SN - 1533-3175

IS - 8

ER -