Optimal Cutoff Scores for Alzheimer's Disease Using the Chinese Version of Mini-Mental State Examination among Chinese Population Living in Rural Areas

Zhao Yang, Hunter K. Holt, Jin Hu Fan, Li Ma, Ying Liu, Wen Chen, Peter Como, Lin Zhang, You Lin Qiao

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

To explore the optimal cutoff score for initial detection of Alzheimer's Disease (AD) through the Chinese version of Mini-Mental State Examination (CMMSE) in rural areas in China, we conducted a cross-sectional study within the Linxian General Population Nutritional Follow-up study. 16,488 eligible cohort members participated in the survey and 881 completed the CMMSE. Among 881 participants, the median age (Interquartile range) was 69.00 (10.00), 634 (71.92%) were female, 657 (74.57%) were illiterate, 35 (3.97%) had 6 years of education or higher, and 295 (33.48%) were diagnosed with AD. By reducing the CMMSE criteria for illiterate to 16 points, primary school to 19 points, and middle school or higher to 23 points, the efficiency of Chinese version of Mini-Mental State Examination can be significantly improved for initial detection of AD in rural areas in China, especially in those nutrition deficient areas.

Original languageEnglish (US)
Pages (from-to)650-657
Number of pages8
JournalAmerican Journal of Alzheimer's Disease and other Dementias
Volume31
Issue number8
DOIs
StatePublished - Dec 1 2016

Keywords

  • Alzheimer's disease
  • Chinese population
  • Chinese version Mini-Mental State Examination
  • cutoff scores
  • ROC analysis
  • rural areas

ASJC Scopus subject areas

  • Clinical Psychology
  • Geriatrics and Gerontology
  • Psychiatry and Mental health

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