Optimal Cutoff Scores for Alzheimer's Disease Using the Chinese Version of Mini-Mental State Examination among Chinese Population Living in Rural Areas

Zhao Yang; Hunter K. Holt; Jin Hu Fan; Li Ma; Ying Liu; Wen Chen; Peter Como; Lin Zhang; You Lin Qiao

doi:10.1177/1533317516662336

Optimal Cutoff Scores for Alzheimer's Disease Using the Chinese Version of Mini-Mental State Examination among Chinese Population Living in Rural Areas

Zhao Yang, Hunter K. Holt, Jin Hu Fan, Li Ma, Ying Liu, Wen Chen, Peter Como, Lin Zhang, You Lin Qiao

Neurology

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

To explore the optimal cutoff score for initial detection of Alzheimer's Disease (AD) through the Chinese version of Mini-Mental State Examination (CMMSE) in rural areas in China, we conducted a cross-sectional study within the Linxian General Population Nutritional Follow-up study. 16,488 eligible cohort members participated in the survey and 881 completed the CMMSE. Among 881 participants, the median age (Interquartile range) was 69.00 (10.00), 634 (71.92%) were female, 657 (74.57%) were illiterate, 35 (3.97%) had 6 years of education or higher, and 295 (33.48%) were diagnosed with AD. By reducing the CMMSE criteria for illiterate to 16 points, primary school to 19 points, and middle school or higher to 23 points, the efficiency of Chinese version of Mini-Mental State Examination can be significantly improved for initial detection of AD in rural areas in China, especially in those nutrition deficient areas.

Original language	English (US)
Pages (from-to)	650-657
Number of pages	8
Journal	American Journal of Alzheimer's Disease and other Dementias
Volume	31
Issue number	8
DOIs	https://doi.org/10.1177/1533317516662336
State	Published - Dec 1 2016

Keywords

Alzheimer's disease
Chinese population
Chinese version Mini-Mental State Examination
cutoff scores
ROC analysis
rural areas

ASJC Scopus subject areas

Clinical Psychology
Geriatrics and Gerontology
Psychiatry and Mental health

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10.1177/1533317516662336

Cite this

Yang, Z., Holt, H. K., Fan, J. H., Ma, L., Liu, Y., Chen, W., Como, P., Zhang, L., & Qiao, Y. L. (2016). Optimal Cutoff Scores for Alzheimer's Disease Using the Chinese Version of Mini-Mental State Examination among Chinese Population Living in Rural Areas. American Journal of Alzheimer's Disease and other Dementias, 31(8), 650-657. https://doi.org/10.1177/1533317516662336

Optimal Cutoff Scores for Alzheimer's Disease Using the Chinese Version of Mini-Mental State Examination among Chinese Population Living in Rural Areas. / Yang, Zhao; Holt, Hunter K.; Fan, Jin Hu; Ma, Li; Liu, Ying; Chen, Wen; Como, Peter; Zhang, Lin; Qiao, You Lin.

In: American Journal of Alzheimer's Disease and other Dementias, Vol. 31, No. 8, 01.12.2016, p. 650-657.

Research output: Contribution to journal › Article › peer-review

Yang, Z, Holt, HK, Fan, JH, Ma, L, Liu, Y, Chen, W, Como, P, Zhang, L & Qiao, YL 2016, 'Optimal Cutoff Scores for Alzheimer's Disease Using the Chinese Version of Mini-Mental State Examination among Chinese Population Living in Rural Areas', American Journal of Alzheimer's Disease and other Dementias, vol. 31, no. 8, pp. 650-657. https://doi.org/10.1177/1533317516662336

Yang, Zhao ; Holt, Hunter K. ; Fan, Jin Hu ; Ma, Li ; Liu, Ying ; Chen, Wen ; Como, Peter ; Zhang, Lin ; Qiao, You Lin. / Optimal Cutoff Scores for Alzheimer's Disease Using the Chinese Version of Mini-Mental State Examination among Chinese Population Living in Rural Areas. In: American Journal of Alzheimer's Disease and other Dementias. 2016 ; Vol. 31, No. 8. pp. 650-657.

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abstract = "To explore the optimal cutoff score for initial detection of Alzheimer's Disease (AD) through the Chinese version of Mini-Mental State Examination (CMMSE) in rural areas in China, we conducted a cross-sectional study within the Linxian General Population Nutritional Follow-up study. 16,488 eligible cohort members participated in the survey and 881 completed the CMMSE. Among 881 participants, the median age (Interquartile range) was 69.00 (10.00), 634 (71.92%) were female, 657 (74.57%) were illiterate, 35 (3.97%) had 6 years of education or higher, and 295 (33.48%) were diagnosed with AD. By reducing the CMMSE criteria for illiterate to 16 points, primary school to 19 points, and middle school or higher to 23 points, the efficiency of Chinese version of Mini-Mental State Examination can be significantly improved for initial detection of AD in rural areas in China, especially in those nutrition deficient areas.",

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Optimal Cutoff Scores for Alzheimer's Disease Using the Chinese Version of Mini-Mental State Examination among Chinese Population Living in Rural Areas

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