Optical coherence imaging of hemodynamics, metabolism, and cell viability during brain injury

Vivek Srinivasan, Shau Poh Chong, Conrad William Merkle, Harsha Radhakrishnan, Conor Leahy

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Pre-clinical quantitative imaging endpoints have been challenging in mouse models of cerebrovascular disease. Here we present optical coherence imaging platforms that can quantify blood flow, capillary perfusion, cellular status, and oxygen extraction based on intrinsic scattering signatures.

Original languageEnglish (US)
Title of host publicationCLEO
Subtitle of host publicationApplications and Technology, CLEO_AT 2014
PublisherOptical Society of American (OSA)
ISBN (Print)9781557529992
StatePublished - Jan 1 2014
EventCLEO: Applications and Technology, CLEO_AT 2014 - San Jose, CA, United States
Duration: Jun 8 2014Jun 13 2014

Other

OtherCLEO: Applications and Technology, CLEO_AT 2014
CountryUnited States
CitySan Jose, CA
Period6/8/146/13/14

Fingerprint

brain damage
hemodynamics
Hemodynamics
metabolism
blood flow
viability
Metabolism
mice
Brain
platforms
Cells
signatures
Capillary flow
Imaging techniques
oxygen
scattering
Blood
Scattering
Oxygen

ASJC Scopus subject areas

  • Instrumentation
  • Atomic and Molecular Physics, and Optics

Cite this

Srinivasan, V., Chong, S. P., Merkle, C. W., Radhakrishnan, H., & Leahy, C. (2014). Optical coherence imaging of hemodynamics, metabolism, and cell viability during brain injury. In CLEO: Applications and Technology, CLEO_AT 2014 Optical Society of American (OSA).

Optical coherence imaging of hemodynamics, metabolism, and cell viability during brain injury. / Srinivasan, Vivek; Chong, Shau Poh; Merkle, Conrad William; Radhakrishnan, Harsha; Leahy, Conor.

CLEO: Applications and Technology, CLEO_AT 2014. Optical Society of American (OSA), 2014.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Srinivasan, V, Chong, SP, Merkle, CW, Radhakrishnan, H & Leahy, C 2014, Optical coherence imaging of hemodynamics, metabolism, and cell viability during brain injury. in CLEO: Applications and Technology, CLEO_AT 2014. Optical Society of American (OSA), CLEO: Applications and Technology, CLEO_AT 2014, San Jose, CA, United States, 6/8/14.
Srinivasan V, Chong SP, Merkle CW, Radhakrishnan H, Leahy C. Optical coherence imaging of hemodynamics, metabolism, and cell viability during brain injury. In CLEO: Applications and Technology, CLEO_AT 2014. Optical Society of American (OSA). 2014
Srinivasan, Vivek ; Chong, Shau Poh ; Merkle, Conrad William ; Radhakrishnan, Harsha ; Leahy, Conor. / Optical coherence imaging of hemodynamics, metabolism, and cell viability during brain injury. CLEO: Applications and Technology, CLEO_AT 2014. Optical Society of American (OSA), 2014.
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