Ophthalmology's botanical heritage

Mark Packer, James D Brandt

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

Many of today's important ophthalmic pharmaceuticals have a rich ethnobotanical history. Solanaceous plants, the source of atropine, have contributed to medical therapy since the beginning of Western civilization. The botanical source of physostigmine played a pivotal role as an ordeal poison in the culture of Old Calabar, West Africa. Native peoples of Amazonia treasured plants containing pilocarpine as panaceas because of their impressive diaphoretic effect. Nineteenth century scientists examining these plants because of their folkloric reputations discovered their active compounds and documented their physiological effects. Ophthalmologists such as Argyll Robertson, Laqueur, and Weber built upon this research to bring these pharmaceuticals into therapeutic use. The ongoing loss of the world's tropical rain forests thereatens to destroy a vast storehouse of untested biological compounds.

Original languageEnglish (US)
Pages (from-to)357-365
Number of pages9
JournalSurvey of Ophthalmology
Volume36
Issue number5
DOIs
StatePublished - 1992

Keywords

  • atropine
  • belladonna
  • eserine
  • ethnomedicine
  • glaucoma
  • jaborandi
  • medicinal plants
  • pharmacology
  • pilocarpine

ASJC Scopus subject areas

  • Ophthalmology

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