Operative Mortality in Women and Men Undergoing Coronary Artery Bypass Grafting (from the California Coronary Artery Bypass Grafting Outcomes Reporting Program)

Radhika Bukkapatnam, Khung Keong Yeo, Zhongmin Li, Ezra A Amsterdam

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Abstract

The comparative operative mortality (OM) in women and men undergoing isolated coronary artery bypass graft surgery (CABG) has not been clarified. Therefore, we evaluated factors related to OM in a large cohort of women and men undergoing isolated CABG. Results from 121 hospitals on patients undergoing isolated CABG in 2003 and 2004 were analyzed according to gender, including demographics, clinical characteristics, and surgical outcome. A total of 10,708 women and 29,669 men had isolated CABG in 2003 to 2004. Observed mortality in women was significantly higher than in men (4.60% vs 2.53%, p <0.0001). Although men had a higher prevalence of >3 diseased coronary arteries and left ventricular dysfunction, women were more likely to be older, diabetic, have stage 3 to 5 chronic kidney disease, chronic lung disease, and nonelective CABG. Women were less likely to receive an internal mammary artery graft. Multivariate analysis indicated that women were at higher risk for OM than men (odds ratio 1.61, 95% confidence interval 1.40 to 1.84). In conclusion, data from the large state-mandated CCORP indicate that women are at increased risk of OM after isolated CABG compared to men, despite adjustment for preoperative risk factors.

Original languageEnglish (US)
Pages (from-to)339-342
Number of pages4
JournalAmerican Journal of Cardiology
Volume105
Issue number3
DOIs
StatePublished - Feb 1 2010

Fingerprint

Coronary Artery Bypass
Mortality
Transplants
Mammary Arteries
Left Ventricular Dysfunction
Chronic Renal Insufficiency
Lung Diseases
Coronary Artery Disease
Chronic Disease
Multivariate Analysis
Odds Ratio
Demography
Confidence Intervals

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

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title = "Operative Mortality in Women and Men Undergoing Coronary Artery Bypass Grafting (from the California Coronary Artery Bypass Grafting Outcomes Reporting Program)",
abstract = "The comparative operative mortality (OM) in women and men undergoing isolated coronary artery bypass graft surgery (CABG) has not been clarified. Therefore, we evaluated factors related to OM in a large cohort of women and men undergoing isolated CABG. Results from 121 hospitals on patients undergoing isolated CABG in 2003 and 2004 were analyzed according to gender, including demographics, clinical characteristics, and surgical outcome. A total of 10,708 women and 29,669 men had isolated CABG in 2003 to 2004. Observed mortality in women was significantly higher than in men (4.60{\%} vs 2.53{\%}, p <0.0001). Although men had a higher prevalence of >3 diseased coronary arteries and left ventricular dysfunction, women were more likely to be older, diabetic, have stage 3 to 5 chronic kidney disease, chronic lung disease, and nonelective CABG. Women were less likely to receive an internal mammary artery graft. Multivariate analysis indicated that women were at higher risk for OM than men (odds ratio 1.61, 95{\%} confidence interval 1.40 to 1.84). In conclusion, data from the large state-mandated CCORP indicate that women are at increased risk of OM after isolated CABG compared to men, despite adjustment for preoperative risk factors.",
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