Open lung biopsy in the critically ill newborn

H. W. Cheu, K. P. Lally, R. Clark, S. Harrell, Donald Null

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Experience with 17 open lung biopsies in critically ill premature neonates was reviewed. Despite their small size, prematurity, and near maximal ventilator requirements, the infants suffered no significant complications. In three cases, an infectious agent was identified. In one case end-stage lung fibrosis associated with persistent (>3 months), severe respiratory failure prompted termination of support. In the remainder of the cases, definitively ruling out infection allowed the confident trial of a course of steroids in an attempt to treat bronchopulmonary dysplasia. Unlike older patients, the definitive diagnosis of no infection in the premature neonate is just as informative as the diagnosis of an infection. Used judiciously, open lung biopsy can be performed in the premature infant with acceptable morbidity and mortality.

Original languageEnglish (US)
Pages (from-to)561-563
Number of pages3
JournalPediatrics
Volume86
Issue number4
StatePublished - Jan 1 1990
Externally publishedYes

Fingerprint

Critical Illness
Newborn Infant
Biopsy
Lung
Infection
Bronchopulmonary Dysplasia
Mechanical Ventilators
Premature Infants
Respiratory Insufficiency
Fibrosis
Steroids
Morbidity
Mortality

Keywords

  • Mycoplasma
  • open lung biopsy
  • preterm neonate

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Cheu, H. W., Lally, K. P., Clark, R., Harrell, S., & Null, D. (1990). Open lung biopsy in the critically ill newborn. Pediatrics, 86(4), 561-563.

Open lung biopsy in the critically ill newborn. / Cheu, H. W.; Lally, K. P.; Clark, R.; Harrell, S.; Null, Donald.

In: Pediatrics, Vol. 86, No. 4, 01.01.1990, p. 561-563.

Research output: Contribution to journalArticle

Cheu, HW, Lally, KP, Clark, R, Harrell, S & Null, D 1990, 'Open lung biopsy in the critically ill newborn', Pediatrics, vol. 86, no. 4, pp. 561-563.
Cheu HW, Lally KP, Clark R, Harrell S, Null D. Open lung biopsy in the critically ill newborn. Pediatrics. 1990 Jan 1;86(4):561-563.
Cheu, H. W. ; Lally, K. P. ; Clark, R. ; Harrell, S. ; Null, Donald. / Open lung biopsy in the critically ill newborn. In: Pediatrics. 1990 ; Vol. 86, No. 4. pp. 561-563.
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