Open fetal surgery for myelomeningocele: A review

Nalin Gupta, Jody A. Farrell, Larry Rand, Charles B. Cauldwell, Diana L Farmer

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

In a recently completed randomized, prospective clinical trial, fetal repair for myelomeningocele was shown to result in reduced rates of hydrocephalus requiring placement of a ventriculoperitoneal shunt, improvement in Chiari malformation Type II, and improvement in neurological function compared with standard postnatal repair. Successful fetal surgery requires the active participation and interaction of several clinical teams. Each group has a specific role, and overlap is often required at different points of the treatment plan. Extensive multispecialty discussions with the patient and family are necessary before informed consent can be obtained. Fetal surgery carries significant risks to the mother and fetus and these must be carefully considered prior to a final treatment decision. This review will summarize the evaluation and treatment of patients undergoing fetal repair for myelomeningocele at one institution.

Original languageEnglish (US)
Pages (from-to)265-273
Number of pages9
JournalJournal of Neurosurgery: Pediatrics
Volume9
Issue number3
DOIs
StatePublished - Mar 2012

Fingerprint

Meningomyelocele
Arnold-Chiari Malformation
Ventriculoperitoneal Shunt
Hydrocephalus
Informed Consent
Fetus
Therapeutics
Randomized Controlled Trials
Mothers

Keywords

  • Chiari malformation type I
  • Fetal surgery
  • Hydrocephalus
  • Myelomeningocele

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery
  • Pediatrics, Perinatology, and Child Health

Cite this

Open fetal surgery for myelomeningocele : A review. / Gupta, Nalin; Farrell, Jody A.; Rand, Larry; Cauldwell, Charles B.; Farmer, Diana L.

In: Journal of Neurosurgery: Pediatrics, Vol. 9, No. 3, 03.2012, p. 265-273.

Research output: Contribution to journalArticle

Gupta, Nalin ; Farrell, Jody A. ; Rand, Larry ; Cauldwell, Charles B. ; Farmer, Diana L. / Open fetal surgery for myelomeningocele : A review. In: Journal of Neurosurgery: Pediatrics. 2012 ; Vol. 9, No. 3. pp. 265-273.
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