Ontogeny of the third component of complement in neonatal swine.

J. W. Tyler, James S Cullor, V. L. Douglas, K. M. Parker, W. L. Smith

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Ontogeny of the third component of complement (C3) was monitored in 10 neonatal swine, using a radial immunodiffusion technique. Significant differences in mean serum C3 concentrations, expressed as percentage of C3 concentration in a pooled standard drawn from 15 adult swine, were not observed between serum samples collected before pigs suckled and at 2 days of age (P = 0.2583). Serum C3 concentrations increased significantly between 2 and 7 days of age (P less than 0.0001) and 7 and 14 days of age (P less than 0.0001). Concentrations comparable with those in adults were observed at 14 days of age and significant changes were not observed thereafter. Acquisition of adult concentrations of C3 appeared to be a function of endogenous production by the neonate, rather than by passive colostral transfer.

Original languageEnglish (US)
Pages (from-to)1141-1144
Number of pages4
JournalAmerican Journal of Veterinary Research
Issue number7
StatePublished - Jul 1989

ASJC Scopus subject areas

  • veterinary(all)


Dive into the research topics of 'Ontogeny of the third component of complement in neonatal swine.'. Together they form a unique fingerprint.

Cite this