Oncology applications: Intraoperative diagnosis of head and neck carcinoma

D Gregory Farwell, Laura Marcu

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide (Howlader et al. 2011; Upile et al. 2009). The estimated new cases of oral cancer exceeded 40,000 in 2012 in the United States alone (NCI 2012). The known risk factors include chronic topical carcinogen exposure from tobacco, alcohol, and betel quid. Since these carcinogens are typically widely exposed to the tissues of the upper aerodigestive tract through smoke inhalation or alcohol ingestion, patients are predisposed to field cancerization and the development of new malignancies adjacent or remote to the initial tumor. A more recent association has been made in the oropharynx with remote high-risk HPV infection and DNA integration of viral oncogenes.

Original languageEnglish (US)
Title of host publicationFluorescence Lifetime Spectroscopy and Imaging
Subtitle of host publicationPrinciples and Applications in Biomedical Diagnostics
PublisherCRC Press
Pages387-397
Number of pages11
ISBN (Electronic)9781439861684
ISBN (Print)9781439861677
DOIs
StatePublished - Jan 1 2014

Fingerprint

Carcinogens
Oncology
carcinogens
Alcohols
Neck
cancer
Head
Carcinoma
Tobacco
alcohols
Smoke
oncogenes
Virus Integration
Tumors
tobacco
ingestion
Neoplasms
Oropharynx
DNA
Mouth Neoplasms

ASJC Scopus subject areas

  • Engineering(all)
  • Physics and Astronomy(all)
  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Farwell, D. G., & Marcu, L. (2014). Oncology applications: Intraoperative diagnosis of head and neck carcinoma. In Fluorescence Lifetime Spectroscopy and Imaging: Principles and Applications in Biomedical Diagnostics (pp. 387-397). CRC Press. https://doi.org/10.1201/b17018

Oncology applications : Intraoperative diagnosis of head and neck carcinoma. / Farwell, D Gregory; Marcu, Laura.

Fluorescence Lifetime Spectroscopy and Imaging: Principles and Applications in Biomedical Diagnostics. CRC Press, 2014. p. 387-397.

Research output: Chapter in Book/Report/Conference proceedingChapter

Farwell, DG & Marcu, L 2014, Oncology applications: Intraoperative diagnosis of head and neck carcinoma. in Fluorescence Lifetime Spectroscopy and Imaging: Principles and Applications in Biomedical Diagnostics. CRC Press, pp. 387-397. https://doi.org/10.1201/b17018
Farwell DG, Marcu L. Oncology applications: Intraoperative diagnosis of head and neck carcinoma. In Fluorescence Lifetime Spectroscopy and Imaging: Principles and Applications in Biomedical Diagnostics. CRC Press. 2014. p. 387-397 https://doi.org/10.1201/b17018
Farwell, D Gregory ; Marcu, Laura. / Oncology applications : Intraoperative diagnosis of head and neck carcinoma. Fluorescence Lifetime Spectroscopy and Imaging: Principles and Applications in Biomedical Diagnostics. CRC Press, 2014. pp. 387-397
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