Abstract
The structure of oceanapiside, an antifungal α,ω-bis- aminohydroxylipid glycoside from the temperate marine sponge Oceanapia sp., was elucidated by a combination of 2D NMR, chemical degradation/ correlation, and MALDI MS-MS spectrometry. Oceanapiside exhibits antifungal activity against Candida glabrata at 10 μg/mL (MIC).
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1678-1681 |
| Number of pages | 4 |
| Journal | Journal of Natural Products |
| Volume | 62 |
| Issue number | 12 |
| DOIs | |
| State | Published - Dec 1999 |
ASJC Scopus subject areas
- Plant Science
- Chemistry (miscellaneous)
- Drug Discovery
- Organic Chemistry
- Pharmacology
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Cite this
Nicholas, G. M., Hong, T. W., Molinski, T. F., Lerch, M. L., Cancilla, M. T., & Lebrilla, C. B. (1999). Oceanapiside, an antifungal bis-α,ω-amino alcohol glycoside from the marine sponge Oceanapia phillipensis. Journal of Natural Products, 62(12), 1678-1681. https://doi.org/10.1021/np990190v