Abstract
Hemoplasmas, the erythrocyte-associated mycoplasmas, have been detected in several primates, causing mostly subclinical infection. This study aimed to determine the prevalence of hemoplasma infection in captive and free-ranging monkeys from southern Brazil, as well as factors and hematological abnormalities associated with infection. Blood samples from 40 non-human primates (NHP) were tested for hemoplasmas and coinfections. An overall of 10/40 (25.0%) NHP tested positive for hemoplasmas using PCR-based assays, including 9/14 (64.3%) black howler monkeys (Alouatta caraya) and 1/24 (4.2%) black-horned capuchin (Sapajus nigritus). Infection was not statistically associated with anemia, but wild-born monkeys and male black howler monkeys were more likely to be positive when compared with captive-born animals and female black howler monkeys, respectively. The sequences from the black howler monkey hemoplasma were similar (94% identity) to the squirrel monkey hemoplasma (“Candidatus Mycoplasma kahanei”) and were phylogenetically located in a different cluster when compared to the human hemoplasma (“Candidatus Mycoplasma haemohominis”).
| Original language | English (US) |
|---|---|
| Pages (from-to) | 6-13 |
| Number of pages | 8 |
| Journal | Comparative Immunology, Microbiology and Infectious Diseases |
| Volume | 52 |
| DOIs | |
| State | Published - Jun 1 2017 |
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Keywords
- Hemoplasma
- Monkey
- Vector-borne disease
- Wild mammal
ASJC Scopus subject areas
- Immunology and Allergy
- Microbiology
- Immunology
- veterinary(all)
- Infectious Diseases
Cite this
Occurrence of hemotropic mycoplasmas in non-human primates (Alouatta caraya, Sapajus nigritus and Callithrix jacchus) of southern Brazil. / Cubilla, Michelle P.; Santos, Leonilda C.; de Moraes, Wanderlei; Cubas, Zalmir S.; Leutenegger, Christian M.; Estrada, Marko; Vieira, Rafael F.C.; Soares, Maurilio J.; Lindsay, Le Ann L.; Sykes, Jane E; Biondo, Alexander W.
In: Comparative Immunology, Microbiology and Infectious Diseases, Vol. 52, 01.06.2017, p. 6-13.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Occurrence of hemotropic mycoplasmas in non-human primates (Alouatta caraya, Sapajus nigritus and Callithrix jacchus) of southern Brazil
AU - Cubilla, Michelle P.
AU - Santos, Leonilda C.
AU - de Moraes, Wanderlei
AU - Cubas, Zalmir S.
AU - Leutenegger, Christian M.
AU - Estrada, Marko
AU - Vieira, Rafael F.C.
AU - Soares, Maurilio J.
AU - Lindsay, Le Ann L.
AU - Sykes, Jane E
AU - Biondo, Alexander W.
PY - 2017/6/1
Y1 - 2017/6/1
N2 - Hemoplasmas, the erythrocyte-associated mycoplasmas, have been detected in several primates, causing mostly subclinical infection. This study aimed to determine the prevalence of hemoplasma infection in captive and free-ranging monkeys from southern Brazil, as well as factors and hematological abnormalities associated with infection. Blood samples from 40 non-human primates (NHP) were tested for hemoplasmas and coinfections. An overall of 10/40 (25.0%) NHP tested positive for hemoplasmas using PCR-based assays, including 9/14 (64.3%) black howler monkeys (Alouatta caraya) and 1/24 (4.2%) black-horned capuchin (Sapajus nigritus). Infection was not statistically associated with anemia, but wild-born monkeys and male black howler monkeys were more likely to be positive when compared with captive-born animals and female black howler monkeys, respectively. The sequences from the black howler monkey hemoplasma were similar (94% identity) to the squirrel monkey hemoplasma (“Candidatus Mycoplasma kahanei”) and were phylogenetically located in a different cluster when compared to the human hemoplasma (“Candidatus Mycoplasma haemohominis”).
AB - Hemoplasmas, the erythrocyte-associated mycoplasmas, have been detected in several primates, causing mostly subclinical infection. This study aimed to determine the prevalence of hemoplasma infection in captive and free-ranging monkeys from southern Brazil, as well as factors and hematological abnormalities associated with infection. Blood samples from 40 non-human primates (NHP) were tested for hemoplasmas and coinfections. An overall of 10/40 (25.0%) NHP tested positive for hemoplasmas using PCR-based assays, including 9/14 (64.3%) black howler monkeys (Alouatta caraya) and 1/24 (4.2%) black-horned capuchin (Sapajus nigritus). Infection was not statistically associated with anemia, but wild-born monkeys and male black howler monkeys were more likely to be positive when compared with captive-born animals and female black howler monkeys, respectively. The sequences from the black howler monkey hemoplasma were similar (94% identity) to the squirrel monkey hemoplasma (“Candidatus Mycoplasma kahanei”) and were phylogenetically located in a different cluster when compared to the human hemoplasma (“Candidatus Mycoplasma haemohominis”).
KW - Hemoplasma
KW - Monkey
KW - Vector-borne disease
KW - Wild mammal
UR - http://www.scopus.com/inward/record.url?scp=85019365316&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85019365316&partnerID=8YFLogxK
U2 - 10.1016/j.cimid.2017.05.002
DO - 10.1016/j.cimid.2017.05.002
M3 - Article
C2 - 28673463
AN - SCOPUS:85019365316
VL - 52
SP - 6
EP - 13
JO - Comparative Immunology, Microbiology and Infectious Diseases
JF - Comparative Immunology, Microbiology and Infectious Diseases
SN - 0147-9571
ER -