Occurrence of hemotropic mycoplasmas in non-human primates (Alouatta caraya, Sapajus nigritus and Callithrix jacchus) of southern Brazil

Michelle P. Cubilla, Leonilda C. Santos, Wanderlei de Moraes, Zalmir S. Cubas, Christian M. Leutenegger, Marko Estrada, Rafael F.C. Vieira, Maurilio J. Soares, Le Ann L. Lindsay, Jane E Sykes, Alexander W. Biondo

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Hemoplasmas, the erythrocyte-associated mycoplasmas, have been detected in several primates, causing mostly subclinical infection. This study aimed to determine the prevalence of hemoplasma infection in captive and free-ranging monkeys from southern Brazil, as well as factors and hematological abnormalities associated with infection. Blood samples from 40 non-human primates (NHP) were tested for hemoplasmas and coinfections. An overall of 10/40 (25.0%) NHP tested positive for hemoplasmas using PCR-based assays, including 9/14 (64.3%) black howler monkeys (Alouatta caraya) and 1/24 (4.2%) black-horned capuchin (Sapajus nigritus). Infection was not statistically associated with anemia, but wild-born monkeys and male black howler monkeys were more likely to be positive when compared with captive-born animals and female black howler monkeys, respectively. The sequences from the black howler monkey hemoplasma were similar (94% identity) to the squirrel monkey hemoplasma (“Candidatus Mycoplasma kahanei”) and were phylogenetically located in a different cluster when compared to the human hemoplasma (“Candidatus Mycoplasma haemohominis”).

Original languageEnglish (US)
Pages (from-to)6-13
Number of pages8
JournalComparative Immunology, Microbiology and Infectious Diseases
Volume52
DOIs
StatePublished - Jun 1 2017

Fingerprint

Alouatta
Callithrix
Callithrix jacchus
Mycoplasma
Primates
Brazil
infection
monkeys
Haplorhini
Infection
Saimiri
mixed infection
Asymptomatic Infections
anemia
Coinfection
erythrocytes
Anemia
Erythrocytes
Alouatta caraya
blood

Keywords

  • Hemoplasma
  • Monkey
  • Vector-borne disease
  • Wild mammal

ASJC Scopus subject areas

  • Immunology and Allergy
  • Microbiology
  • Immunology
  • veterinary(all)
  • Infectious Diseases

Cite this

Occurrence of hemotropic mycoplasmas in non-human primates (Alouatta caraya, Sapajus nigritus and Callithrix jacchus) of southern Brazil. / Cubilla, Michelle P.; Santos, Leonilda C.; de Moraes, Wanderlei; Cubas, Zalmir S.; Leutenegger, Christian M.; Estrada, Marko; Vieira, Rafael F.C.; Soares, Maurilio J.; Lindsay, Le Ann L.; Sykes, Jane E; Biondo, Alexander W.

In: Comparative Immunology, Microbiology and Infectious Diseases, Vol. 52, 01.06.2017, p. 6-13.

Research output: Contribution to journalArticle

Cubilla, Michelle P. ; Santos, Leonilda C. ; de Moraes, Wanderlei ; Cubas, Zalmir S. ; Leutenegger, Christian M. ; Estrada, Marko ; Vieira, Rafael F.C. ; Soares, Maurilio J. ; Lindsay, Le Ann L. ; Sykes, Jane E ; Biondo, Alexander W. / Occurrence of hemotropic mycoplasmas in non-human primates (Alouatta caraya, Sapajus nigritus and Callithrix jacchus) of southern Brazil. In: Comparative Immunology, Microbiology and Infectious Diseases. 2017 ; Vol. 52. pp. 6-13.
@article{2d0ab47a3a4f450eba1a6418aa8baa44,
title = "Occurrence of hemotropic mycoplasmas in non-human primates (Alouatta caraya, Sapajus nigritus and Callithrix jacchus) of southern Brazil",
abstract = "Hemoplasmas, the erythrocyte-associated mycoplasmas, have been detected in several primates, causing mostly subclinical infection. This study aimed to determine the prevalence of hemoplasma infection in captive and free-ranging monkeys from southern Brazil, as well as factors and hematological abnormalities associated with infection. Blood samples from 40 non-human primates (NHP) were tested for hemoplasmas and coinfections. An overall of 10/40 (25.0{\%}) NHP tested positive for hemoplasmas using PCR-based assays, including 9/14 (64.3{\%}) black howler monkeys (Alouatta caraya) and 1/24 (4.2{\%}) black-horned capuchin (Sapajus nigritus). Infection was not statistically associated with anemia, but wild-born monkeys and male black howler monkeys were more likely to be positive when compared with captive-born animals and female black howler monkeys, respectively. The sequences from the black howler monkey hemoplasma were similar (94{\%} identity) to the squirrel monkey hemoplasma (“Candidatus Mycoplasma kahanei”) and were phylogenetically located in a different cluster when compared to the human hemoplasma (“Candidatus Mycoplasma haemohominis”).",
keywords = "Hemoplasma, Monkey, Vector-borne disease, Wild mammal",
author = "Cubilla, {Michelle P.} and Santos, {Leonilda C.} and {de Moraes}, Wanderlei and Cubas, {Zalmir S.} and Leutenegger, {Christian M.} and Marko Estrada and Vieira, {Rafael F.C.} and Soares, {Maurilio J.} and Lindsay, {Le Ann L.} and Sykes, {Jane E} and Biondo, {Alexander W.}",
year = "2017",
month = "6",
day = "1",
doi = "10.1016/j.cimid.2017.05.002",
language = "English (US)",
volume = "52",
pages = "6--13",
journal = "Comparative Immunology, Microbiology and Infectious Diseases",
issn = "0147-9571",
publisher = "Elsevier Limited",

}

TY - JOUR

T1 - Occurrence of hemotropic mycoplasmas in non-human primates (Alouatta caraya, Sapajus nigritus and Callithrix jacchus) of southern Brazil

AU - Cubilla, Michelle P.

AU - Santos, Leonilda C.

AU - de Moraes, Wanderlei

AU - Cubas, Zalmir S.

AU - Leutenegger, Christian M.

AU - Estrada, Marko

AU - Vieira, Rafael F.C.

AU - Soares, Maurilio J.

AU - Lindsay, Le Ann L.

AU - Sykes, Jane E

AU - Biondo, Alexander W.

PY - 2017/6/1

Y1 - 2017/6/1

N2 - Hemoplasmas, the erythrocyte-associated mycoplasmas, have been detected in several primates, causing mostly subclinical infection. This study aimed to determine the prevalence of hemoplasma infection in captive and free-ranging monkeys from southern Brazil, as well as factors and hematological abnormalities associated with infection. Blood samples from 40 non-human primates (NHP) were tested for hemoplasmas and coinfections. An overall of 10/40 (25.0%) NHP tested positive for hemoplasmas using PCR-based assays, including 9/14 (64.3%) black howler monkeys (Alouatta caraya) and 1/24 (4.2%) black-horned capuchin (Sapajus nigritus). Infection was not statistically associated with anemia, but wild-born monkeys and male black howler monkeys were more likely to be positive when compared with captive-born animals and female black howler monkeys, respectively. The sequences from the black howler monkey hemoplasma were similar (94% identity) to the squirrel monkey hemoplasma (“Candidatus Mycoplasma kahanei”) and were phylogenetically located in a different cluster when compared to the human hemoplasma (“Candidatus Mycoplasma haemohominis”).

AB - Hemoplasmas, the erythrocyte-associated mycoplasmas, have been detected in several primates, causing mostly subclinical infection. This study aimed to determine the prevalence of hemoplasma infection in captive and free-ranging monkeys from southern Brazil, as well as factors and hematological abnormalities associated with infection. Blood samples from 40 non-human primates (NHP) were tested for hemoplasmas and coinfections. An overall of 10/40 (25.0%) NHP tested positive for hemoplasmas using PCR-based assays, including 9/14 (64.3%) black howler monkeys (Alouatta caraya) and 1/24 (4.2%) black-horned capuchin (Sapajus nigritus). Infection was not statistically associated with anemia, but wild-born monkeys and male black howler monkeys were more likely to be positive when compared with captive-born animals and female black howler monkeys, respectively. The sequences from the black howler monkey hemoplasma were similar (94% identity) to the squirrel monkey hemoplasma (“Candidatus Mycoplasma kahanei”) and were phylogenetically located in a different cluster when compared to the human hemoplasma (“Candidatus Mycoplasma haemohominis”).

KW - Hemoplasma

KW - Monkey

KW - Vector-borne disease

KW - Wild mammal

UR - http://www.scopus.com/inward/record.url?scp=85019365316&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85019365316&partnerID=8YFLogxK

U2 - 10.1016/j.cimid.2017.05.002

DO - 10.1016/j.cimid.2017.05.002

M3 - Article

C2 - 28673463

AN - SCOPUS:85019365316

VL - 52

SP - 6

EP - 13

JO - Comparative Immunology, Microbiology and Infectious Diseases

JF - Comparative Immunology, Microbiology and Infectious Diseases

SN - 0147-9571

ER -