Abstract
The studies reviewed in this article indicate the association of occupational exposure to a variety of organic and inorganic dusts and various gases and fumes with chronic bronchitis and decrements in FEV1. Usually an obstructive pattern was noted, although in some occupations a similar decrement in FVC was noted. The effect of smoking on chronic bronchitis, respiratory symptoms, and FEV1 was usually additive, although workers exposed to cotton dust in one study demonstrated an interaction between exposure and smoking, as did a study of a general population sample. In coal workers, exposure to dust in younger workers resulted in a greater decline in lung function than if the exposure occurred in older workers. Studies in coal miners and grain workers further suggest that occupational standards in effect are not sufficient to protect the working population from adverse effects. The magnitude of the effect of occupation on decrement in FEV1 is usually less than cigarette smoking. Studies in coal miners indicate, however, that a minority of workers could be more severely affected by exposure. When considered together with cigarette smoking, additional decrements in lung function because of occupational exposure could contribute to disability. Additional study is needed for better understanding of exposure-response relationships, host factors, potential interaction with cigarette smoking, and the pathophysiology of the development of occupationally induced airway disease.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 851-878 |
| Number of pages | 28 |
| Journal | Medical Clinics of North America |
| Volume | 80 |
| Issue number | 4 |
| DOIs | |
| State | Published - 1996 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Medicine(all)
Cite this
Occupationally induced airways obstruction. / Garshick, E.; Schenker, Marc B; Dosman, J. A.
In: Medical Clinics of North America, Vol. 80, No. 4, 1996, p. 851-878.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Occupationally induced airways obstruction
AU - Garshick, E.
AU - Schenker, Marc B
AU - Dosman, J. A.
PY - 1996
Y1 - 1996
N2 - The studies reviewed in this article indicate the association of occupational exposure to a variety of organic and inorganic dusts and various gases and fumes with chronic bronchitis and decrements in FEV1. Usually an obstructive pattern was noted, although in some occupations a similar decrement in FVC was noted. The effect of smoking on chronic bronchitis, respiratory symptoms, and FEV1 was usually additive, although workers exposed to cotton dust in one study demonstrated an interaction between exposure and smoking, as did a study of a general population sample. In coal workers, exposure to dust in younger workers resulted in a greater decline in lung function than if the exposure occurred in older workers. Studies in coal miners and grain workers further suggest that occupational standards in effect are not sufficient to protect the working population from adverse effects. The magnitude of the effect of occupation on decrement in FEV1 is usually less than cigarette smoking. Studies in coal miners indicate, however, that a minority of workers could be more severely affected by exposure. When considered together with cigarette smoking, additional decrements in lung function because of occupational exposure could contribute to disability. Additional study is needed for better understanding of exposure-response relationships, host factors, potential interaction with cigarette smoking, and the pathophysiology of the development of occupationally induced airway disease.
AB - The studies reviewed in this article indicate the association of occupational exposure to a variety of organic and inorganic dusts and various gases and fumes with chronic bronchitis and decrements in FEV1. Usually an obstructive pattern was noted, although in some occupations a similar decrement in FVC was noted. The effect of smoking on chronic bronchitis, respiratory symptoms, and FEV1 was usually additive, although workers exposed to cotton dust in one study demonstrated an interaction between exposure and smoking, as did a study of a general population sample. In coal workers, exposure to dust in younger workers resulted in a greater decline in lung function than if the exposure occurred in older workers. Studies in coal miners and grain workers further suggest that occupational standards in effect are not sufficient to protect the working population from adverse effects. The magnitude of the effect of occupation on decrement in FEV1 is usually less than cigarette smoking. Studies in coal miners indicate, however, that a minority of workers could be more severely affected by exposure. When considered together with cigarette smoking, additional decrements in lung function because of occupational exposure could contribute to disability. Additional study is needed for better understanding of exposure-response relationships, host factors, potential interaction with cigarette smoking, and the pathophysiology of the development of occupationally induced airway disease.
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UR - http://www.scopus.com/inward/citedby.url?scp=0029899555&partnerID=8YFLogxK
U2 - 10.1016/S0025-7125(05)70470-3
DO - 10.1016/S0025-7125(05)70470-3
M3 - Article
C2 - 8676617
AN - SCOPUS:0029899555
VL - 80
SP - 851
EP - 878
JO - Medical Clinics of North America
JF - Medical Clinics of North America
SN - 0025-7125
IS - 4
ER -