Observations on the dose-response curve for arsenic exposure and lung cancer

Research output: Chapter in Book/Report/Conference proceedingChapter

66 Scopus citations


Occupational studies in three countries have related quantitative estimates of arsenic exposure to lung cancer risks. Mine exposures in China appear to incur a higher relative risk than arsenic exposures elsewhere. Two studies are also consistent with a linear relationship over an elevated background risk of lung cancer among arsenic-exposed workers. Plausible explanations include synergism (with smoking) which varies in magnitude according to the level of arsenic exposure, long-term survivorship in higher exposure jobs among the healthier, less susceptible individuals, exposure estimate errors that were more prominent at higher exposure levels as a result of past industrial hygiene sampling or worker protection practices. -from Authors

Original languageEnglish (US)
Title of host publicationScandinavian Journal of Work, Environment & Health
Number of pages10
StatePublished - 1993
Externally publishedYes

ASJC Scopus subject areas

  • Environmental Science(all)
  • Earth and Planetary Sciences(all)
  • Health, Toxicology and Mutagenesis
  • Public Health, Environmental and Occupational Health
  • Toxicology
  • Geography, Planning and Development


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