Oblique-incidence reflectivity difference microscopes for label-free high-throughput detection of biochemical reactions in microarray format

X. D. Zhu; J. P. Landry; Y. S. Sun; Jeffrey Gregg; Kit Lam; X. W. Guo

Oblique-incidence reflectivity difference microscopes for label-free high-throughput detection of biochemical reactions in microarray format

X. D. Zhu, J. P. Landry, Y. S. Sun, Jeffrey Gregg, Kit Lam, X. W. Guo

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

We describe recently developed oblique-incidence optical reflectivity difference microscopes for label-free/high-throughput detection of biomolecular reactions on DNA/protein microarrays. We present examples of application of this technique to DNA-DNA hybridization, antibody-antigen capture, and protein-small-molecule binding reactions.

Original language	English (US)
Title of host publication	Optics InfoBase Conference Papers
Publisher	Optical Society of America
ISBN (Print)	1557528071, 9781557528070
State	Published - 2006
Event	Biomedical Topical Meeting, BIO 2006 - Fort Lauderdale, FL, United States Duration: Mar 19 2006 → Mar 19 2006

Other

Other	Biomedical Topical Meeting, BIO 2006
Country/Territory	United States
City	Fort Lauderdale, FL
Period	3/19/06 → 3/19/06

ASJC Scopus subject areas

Instrumentation
Atomic and Molecular Physics, and Optics

Cite this

Oblique-incidence reflectivity difference microscopes for label-free high-throughput detection of biochemical reactions in microarray format. / Zhu, X. D.; Landry, J. P.; Sun, Y. S.; Gregg, Jeffrey ; Lam, Kit; Guo, X. W.

Optics InfoBase Conference Papers. Optical Society of America, 2006.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

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abstract = "We describe recently developed oblique-incidence optical reflectivity difference microscopes for label-free/high-throughput detection of biomolecular reactions on DNA/protein microarrays. We present examples of application of this technique to DNA-DNA hybridization, antibody-antigen capture, and protein-small-molecule binding reactions.",

author = "Zhu, {X. D.} and Landry, {J. P.} and Sun, {Y. S.} and Jeffrey Gregg and Kit Lam and Guo, {X. W.}",

year = "2006",

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AU - Zhu, X. D.

AU - Landry, J. P.

AU - Sun, Y. S.

AU - Gregg, Jeffrey

AU - Lam, Kit

AU - Guo, X. W.

PY - 2006

Y1 - 2006

N2 - We describe recently developed oblique-incidence optical reflectivity difference microscopes for label-free/high-throughput detection of biomolecular reactions on DNA/protein microarrays. We present examples of application of this technique to DNA-DNA hybridization, antibody-antigen capture, and protein-small-molecule binding reactions.

AB - We describe recently developed oblique-incidence optical reflectivity difference microscopes for label-free/high-throughput detection of biomolecular reactions on DNA/protein microarrays. We present examples of application of this technique to DNA-DNA hybridization, antibody-antigen capture, and protein-small-molecule binding reactions.

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UR - http://www.scopus.com/inward/citedby.url?scp=84899151627&partnerID=8YFLogxK

M3 - Conference contribution

AN - SCOPUS:84899151627

SN - 1557528071

SN - 9781557528070

BT - Optics InfoBase Conference Papers

PB - Optical Society of America

T2 - Biomedical Topical Meeting, BIO 2006

Y2 - 19 March 2006 through 19 March 2006

ER -

Oblique-incidence reflectivity difference microscopes for label-free high-throughput detection of biochemical reactions in microarray format

Abstract

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ASJC Scopus subject areas

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