Abstract
We describe recently developed oblique-incidence optical reflectivity difference microscopes for label-free/high-throughput detection of biomolecular reactions on DNA/protein microarrays. We present examples of application of this technique to DNA-DNA hybridization, antibody-antigen capture, and protein-small-molecule binding reactions.
Original language | English (US) |
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Title of host publication | Optics InfoBase Conference Papers |
Publisher | Optical Society of America |
ISBN (Print) | 1557528071, 9781557528070 |
State | Published - 2006 |
Event | Biomedical Topical Meeting, BIO 2006 - Fort Lauderdale, FL, United States Duration: Mar 19 2006 → Mar 19 2006 |
Other
Other | Biomedical Topical Meeting, BIO 2006 |
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Country/Territory | United States |
City | Fort Lauderdale, FL |
Period | 3/19/06 → 3/19/06 |
ASJC Scopus subject areas
- Instrumentation
- Atomic and Molecular Physics, and Optics