Oblique-incidence reflectivity difference microscopes for label-free high-throughput detection of biochemical reactions in microarray format

X. D. Zhu; J. P. Landry; Y. S. Sun; Jeffrey Gregg; Kit Lam; X. W. Guo

Oblique-incidence reflectivity difference microscopes for label-free high-throughput detection of biochemical reactions in microarray format

X. D. Zhu, J. P. Landry, Y. S. Sun, Jeffrey Gregg, Kit Lam, X. W. Guo

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

We describe recently developed oblique-incidence optical reflectivity difference microscopes for label-free/high-throughput detection of biomolecular reactions on DNA/protein microarrays. We present examples of application of this technique to DNA-DNA hybridization, antibody-antigen capture, and protein-small-molecule binding reactions.

Original language	English (US)
Title of host publication	Optics InfoBase Conference Papers
Publisher	Optical Society of America
ISBN (Print)	1557528071, 9781557528070
State	Published - 2006
Event	Biomedical Topical Meeting, BIO 2006 - Fort Lauderdale, FL, United States Duration: Mar 19 2006 → Mar 19 2006

Other

Other	Biomedical Topical Meeting, BIO 2006
Country	United States
City	Fort Lauderdale, FL
Period	3/19/06 → 3/19/06

ASJC Scopus subject areas

Instrumentation
Atomic and Molecular Physics, and Optics

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Oblique-incidence reflectivity difference microscopes for label-free high-throughput detection of biochemical reactions in microarray format. / Zhu, X. D.; Landry, J. P.; Sun, Y. S.; Gregg, Jeffrey ; Lam, Kit; Guo, X. W.

Optics InfoBase Conference Papers. Optical Society of America, 2006.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

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abstract = "We describe recently developed oblique-incidence optical reflectivity difference microscopes for label-free/high-throughput detection of biomolecular reactions on DNA/protein microarrays. We present examples of application of this technique to DNA-DNA hybridization, antibody-antigen capture, and protein-small-molecule binding reactions.",

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AU - Gregg, Jeffrey

AU - Lam, Kit

AU - Guo, X. W.

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