Obligatory transformation of fibroblasts by bone matrix in rats fed sucrose ration

A Hari Reddi, C. B. Huggins

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Allogeneic transplantation of coarse powder of demineralized bone matrix in rats has a profound influence on the gene expression of responding fibroblasts. Under normal nutritional states, the fibroblasts are transformed sequentially into cartilage and bone with hemopoietic bone marrow. In rats fed sucrose exclusively, there was an obligatory transformation of fibroblasts to cartilage and bone. However, there was no evidence of erythropoiesis.

Original languageEnglish (US)
Pages (from-to)475-478
Number of pages4
JournalProceedings of the Society for Experimental Biology and Medicine
Volume145
Issue number2
StatePublished - 1974
Externally publishedYes

Fingerprint

Bone Matrix
Fibroblasts
Sucrose
Rats
Bone
Cartilage
Bone and Bones
Erythropoiesis
Homologous Transplantation
Powders
Bone Marrow
Gene expression
Gene Expression

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Obligatory transformation of fibroblasts by bone matrix in rats fed sucrose ration. / Reddi, A Hari; Huggins, C. B.

In: Proceedings of the Society for Experimental Biology and Medicine, Vol. 145, No. 2, 1974, p. 475-478.

Research output: Contribution to journalArticle

@article{3b69abecabda402faa71d9cb9a2bcd81,
title = "Obligatory transformation of fibroblasts by bone matrix in rats fed sucrose ration",
abstract = "Allogeneic transplantation of coarse powder of demineralized bone matrix in rats has a profound influence on the gene expression of responding fibroblasts. Under normal nutritional states, the fibroblasts are transformed sequentially into cartilage and bone with hemopoietic bone marrow. In rats fed sucrose exclusively, there was an obligatory transformation of fibroblasts to cartilage and bone. However, there was no evidence of erythropoiesis.",
author = "Reddi, {A Hari} and Huggins, {C. B.}",
year = "1974",
language = "English (US)",
volume = "145",
pages = "475--478",
journal = "Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N. Y.)",
issn = "1535-3702",
publisher = "Society for Experimental Biology and Medicine",
number = "2",

}

TY - JOUR

T1 - Obligatory transformation of fibroblasts by bone matrix in rats fed sucrose ration

AU - Reddi, A Hari

AU - Huggins, C. B.

PY - 1974

Y1 - 1974

N2 - Allogeneic transplantation of coarse powder of demineralized bone matrix in rats has a profound influence on the gene expression of responding fibroblasts. Under normal nutritional states, the fibroblasts are transformed sequentially into cartilage and bone with hemopoietic bone marrow. In rats fed sucrose exclusively, there was an obligatory transformation of fibroblasts to cartilage and bone. However, there was no evidence of erythropoiesis.

AB - Allogeneic transplantation of coarse powder of demineralized bone matrix in rats has a profound influence on the gene expression of responding fibroblasts. Under normal nutritional states, the fibroblasts are transformed sequentially into cartilage and bone with hemopoietic bone marrow. In rats fed sucrose exclusively, there was an obligatory transformation of fibroblasts to cartilage and bone. However, there was no evidence of erythropoiesis.

UR - http://www.scopus.com/inward/record.url?scp=0015949146&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0015949146&partnerID=8YFLogxK

M3 - Article

C2 - 4273395

AN - SCOPUS:0015949146

VL - 145

SP - 475

EP - 478

JO - Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N. Y.)

JF - Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N. Y.)

SN - 1535-3702

IS - 2

ER -