Obligatory transformation of fibroblasts by bone matrix in rats fed sucrose ration

A Hari Reddi, C. B. Huggins

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

Allogeneic transplantation of coarse powder of demineralized bone matrix in rats has a profound influence on the gene expression of responding fibroblasts. Under normal nutritional states, the fibroblasts are transformed sequentially into cartilage and bone with hemopoietic bone marrow. In rats fed sucrose exclusively, there was an obligatory transformation of fibroblasts to cartilage and bone. However, there was no evidence of erythropoiesis.

Original languageEnglish (US)
Pages (from-to)475-478
Number of pages4
JournalProceedings of the Society for Experimental Biology and Medicine
Volume145
Issue number2
StatePublished - 1974
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Fingerprint Dive into the research topics of 'Obligatory transformation of fibroblasts by bone matrix in rats fed sucrose ration'. Together they form a unique fingerprint.

  • Cite this