Abstract
Allogeneic transplantation of coarse powder of demineralized bone matrix in rats has a profound influence on the gene expression of responding fibroblasts. Under normal nutritional states, the fibroblasts are transformed sequentially into cartilage and bone with hemopoietic bone marrow. In rats fed sucrose exclusively, there was an obligatory transformation of fibroblasts to cartilage and bone. However, there was no evidence of erythropoiesis.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 475-478 |
| Number of pages | 4 |
| Journal | Proceedings of the Society for Experimental Biology and Medicine |
| Volume | 145 |
| Issue number | 2 |
| State | Published - 1974 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
Cite this
Obligatory transformation of fibroblasts by bone matrix in rats fed sucrose ration. / Reddi, A Hari; Huggins, C. B.
In: Proceedings of the Society for Experimental Biology and Medicine, Vol. 145, No. 2, 1974, p. 475-478.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Obligatory transformation of fibroblasts by bone matrix in rats fed sucrose ration
AU - Reddi, A Hari
AU - Huggins, C. B.
PY - 1974
Y1 - 1974
N2 - Allogeneic transplantation of coarse powder of demineralized bone matrix in rats has a profound influence on the gene expression of responding fibroblasts. Under normal nutritional states, the fibroblasts are transformed sequentially into cartilage and bone with hemopoietic bone marrow. In rats fed sucrose exclusively, there was an obligatory transformation of fibroblasts to cartilage and bone. However, there was no evidence of erythropoiesis.
AB - Allogeneic transplantation of coarse powder of demineralized bone matrix in rats has a profound influence on the gene expression of responding fibroblasts. Under normal nutritional states, the fibroblasts are transformed sequentially into cartilage and bone with hemopoietic bone marrow. In rats fed sucrose exclusively, there was an obligatory transformation of fibroblasts to cartilage and bone. However, there was no evidence of erythropoiesis.
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UR - http://www.scopus.com/inward/citedby.url?scp=0015949146&partnerID=8YFLogxK
M3 - Article
C2 - 4273395
AN - SCOPUS:0015949146
VL - 145
SP - 475
EP - 478
JO - Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N. Y.)
JF - Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N. Y.)
SN - 1535-3702
IS - 2
ER -