Nutritional adequacy of a comprehensive nutrition program in patients with generalized cardiovascular metabolic disease

J. S. Stern, J. A. Men

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The objective of this study was to determine the health effects and nutritional adequacy of two dietary interventions designed to treat individuals with marginally controlled hypertension, dyslipidemia or NIDDM. In a multicenter trial, 560 subjects aged 25-70 were randomized to one of the following intervention groups: 1) a nutritionist-guided selfselected mixed-food meal plan (n=277) or, 2) a proprietary prepared nutrient-fortified meal plan (n=283). Both meal plans provided as % kcal < 20% fat, 15-20% protein and 55-60% carbohydrate. Dietary intake was estimated with 3-day food records throughout the 10 week intervention period. The prepared diet group exceeded all USRDAs whereas the self-selected diet group failed to meet the USRDAs for the following nutrients (reported as % USRDA): USBEA ErenaffiJ Self-selected ♀ ♂ ♀ ♂ folie acid (μg) 400 161 187 76 101 vitamin E (IU) 30 126 146 62 81 calcium (mg) 1000 172 213 79 103 magnesium (mg) 400 142 173 72 97 zinc(mg) 15 161 190 60 83 vitamin B12 (μg) 6.0 194 238 64 99 Subjects on the prepared meal plan reported greater intakes of dietary fiber, iron, vitamins B,.3, copper, paotothenic acid and potassium, and lower levels of sodium and % kcal from fat (p<0.001). In conclusion, standard dietary prescriptions fail to meet important nutrient recommendations for disease-modifying nutrients, particularly for women. The optimal nutrient composition of the prepared meal plan is an effective modality for meeting nutrient recommendations for treatment of chronic diseases.

Original languageEnglish (US)
JournalFASEB Journal
Issue number3
StatePublished - 1996

ASJC Scopus subject areas

  • Agricultural and Biological Sciences (miscellaneous)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Biochemistry
  • Cell Biology


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