Abstract
It is well recognized that lipid in the intestine is a potent inhibitor of gastric secretomotor function. Progress has been made in the identification of the 'sensor' for lipid in the intestinal wall. Long-chain free fatty acids are the stimulus both for release of CCK and for the production of functional effects. Long-chain triglyceride requires chylomicron formation for absorption, and there is strong evidence that the postabsorptive products of long-chain triglyceride absorption, including chylomicrons and apolipoproteins, are involved in sensory transduction in the intestinal wall.
Original language | English (US) |
---|---|
Journal | American Journal of Physiology - Gastrointestinal and Liver Physiology |
Volume | 277 |
Issue number | 4 40-4 |
State | Published - 1999 |
Externally published | Yes |
Keywords
- Cholecystokinin A receptors
- Chylomicrons
- Long-chain fatty acids
- Vagal afferents
ASJC Scopus subject areas
- Gastroenterology
- Physiology
- Physiology (medical)