Nuclear medicine has a major role in the management of malignant tumors. With the developments towards molecular imaging and the technological advancement of scanners providing a fusion of both physiologic and anatomic imaging, it has even become a more integral part of management protocols. This role includes detection of malignant tumors, staging and restaging of the disease, early detection of recurrence, evaluation of the response to therapy, and prediction of the prognosis. Radionuclide diagnosis and therapy for tumors depend on the characteristics of tumors including increased vascularization, increased blood fl ow, newly proliferated capillaries with more permeable walls, increased metabolic activity of cells, increased energy demand, high density of some common antigens or several specifi c antigens, and several specifi c receptors as discussed in the previous chapter.
|Original language||English (US)|
|Title of host publication||The Pathophysiologic Basis of Nuclear Medicine|
|Publisher||Springer International Publishing|
|Number of pages||31|
|State||Published - Jan 1 2015|
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)