Abstract
Immunogenic peptides containing epitopes of the gp120 C4 and V3 regions from human immunodeficiency virus strains MN and EV91 have been studied by nuclear magnetic resonance and molecular modeling and used as immunogens in rhesus monkeys. The results, combined with those for other peptides, suggest a correlation between solution conformation and immunologic cross-reactivity.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 746-750 |
| Number of pages | 5 |
| Journal | Journal of Virology |
| Volume | 73 |
| Issue number | 1 |
| State | Published - 1999 |
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ASJC Scopus subject areas
- Immunology
Cite this
Nuclear magnetic resonance analysis of solution conformations in C4-V3 hybrid peptides derived from human immunodeficiency virus (HIV) type 1 gp120 : Relation to specificity of peptide-induced anti-HIV neutralizing antibodies. / Vu, Hai M.; Myers, David; De Lorimier, Robert; Matthews, Thomas J.; Anthony Moody, M.; Heinly, Craig; Torres, Jose V; Haynes, Barton F.; Spicer, Leonard.
In: Journal of Virology, Vol. 73, No. 1, 1999, p. 746-750.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Nuclear magnetic resonance analysis of solution conformations in C4-V3 hybrid peptides derived from human immunodeficiency virus (HIV) type 1 gp120
T2 - Relation to specificity of peptide-induced anti-HIV neutralizing antibodies
AU - Vu, Hai M.
AU - Myers, David
AU - De Lorimier, Robert
AU - Matthews, Thomas J.
AU - Anthony Moody, M.
AU - Heinly, Craig
AU - Torres, Jose V
AU - Haynes, Barton F.
AU - Spicer, Leonard
PY - 1999
Y1 - 1999
N2 - Immunogenic peptides containing epitopes of the gp120 C4 and V3 regions from human immunodeficiency virus strains MN and EV91 have been studied by nuclear magnetic resonance and molecular modeling and used as immunogens in rhesus monkeys. The results, combined with those for other peptides, suggest a correlation between solution conformation and immunologic cross-reactivity.
AB - Immunogenic peptides containing epitopes of the gp120 C4 and V3 regions from human immunodeficiency virus strains MN and EV91 have been studied by nuclear magnetic resonance and molecular modeling and used as immunogens in rhesus monkeys. The results, combined with those for other peptides, suggest a correlation between solution conformation and immunologic cross-reactivity.
UR - http://www.scopus.com/inward/record.url?scp=0032889455&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0032889455&partnerID=8YFLogxK
M3 - Article
VL - 73
SP - 746
EP - 750
JO - Journal of Virology
JF - Journal of Virology
SN - 0022-538X
IS - 1
ER -