Nuclear magnetic resonance analysis of solution conformations in C4-V3 hybrid peptides derived from human immunodeficiency virus (HIV) type 1 gp120: Relation to specificity of peptide-induced anti-HIV neutralizing antibodies

Hai M. Vu; David Myers; Robert De Lorimier; Thomas J. Matthews; M. Anthony Moody; Craig Heinly; Jose V Torres; Barton F. Haynes; Leonard Spicer

Nuclear magnetic resonance analysis of solution conformations in C4-V3 hybrid peptides derived from human immunodeficiency virus (HIV) type 1 gp120: Relation to specificity of peptide-induced anti-HIV neutralizing antibodies

Hai M. Vu, David Myers, Robert De Lorimier, Thomas J. Matthews, M. Anthony Moody, Craig Heinly, Jose V Torres, Barton F. Haynes, Leonard Spicer

Medical Microbiology and Immunology

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

Immunogenic peptides containing epitopes of the gp120 C4 and V3 regions from human immunodeficiency virus strains MN and EV91 have been studied by nuclear magnetic resonance and molecular modeling and used as immunogens in rhesus monkeys. The results, combined with those for other peptides, suggest a correlation between solution conformation and immunologic cross-reactivity.

Original language	English (US)
Pages (from-to)	746-750
Number of pages	5
Journal	Journal of Virology
Volume	73
Issue number	1
State	Published - 1999

ASJC Scopus subject areas

Immunology

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Vu, H. M., Myers, D., De Lorimier, R., Matthews, T. J., Anthony Moody, M., Heinly, C., Torres, J. V., Haynes, B. F., & Spicer, L. (1999). Nuclear magnetic resonance analysis of solution conformations in C4-V3 hybrid peptides derived from human immunodeficiency virus (HIV) type 1 gp120: Relation to specificity of peptide-induced anti-HIV neutralizing antibodies. Journal of Virology, 73(1), 746-750.

Nuclear magnetic resonance analysis of solution conformations in C4-V3 hybrid peptides derived from human immunodeficiency virus (HIV) type 1 gp120 : Relation to specificity of peptide-induced anti-HIV neutralizing antibodies. / Vu, Hai M.; Myers, David; De Lorimier, Robert; Matthews, Thomas J.; Anthony Moody, M.; Heinly, Craig; Torres, Jose V; Haynes, Barton F.; Spicer, Leonard.

In: Journal of Virology, Vol. 73, No. 1, 1999, p. 746-750.

Research output: Contribution to journal › Article › peer-review

Vu, HM, Myers, D, De Lorimier, R, Matthews, TJ, Anthony Moody, M, Heinly, C, Torres, JV, Haynes, BF & Spicer, L 1999, 'Nuclear magnetic resonance analysis of solution conformations in C4-V3 hybrid peptides derived from human immunodeficiency virus (HIV) type 1 gp120: Relation to specificity of peptide-induced anti-HIV neutralizing antibodies', Journal of Virology, vol. 73, no. 1, pp. 746-750.

Vu, Hai M. ; Myers, David ; De Lorimier, Robert ; Matthews, Thomas J. ; Anthony Moody, M. ; Heinly, Craig ; Torres, Jose V ; Haynes, Barton F. ; Spicer, Leonard. / Nuclear magnetic resonance analysis of solution conformations in C4-V3 hybrid peptides derived from human immunodeficiency virus (HIV) type 1 gp120 : Relation to specificity of peptide-induced anti-HIV neutralizing antibodies. In: Journal of Virology. 1999 ; Vol. 73, No. 1. pp. 746-750.

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Nuclear magnetic resonance analysis of solution conformations in C4-V3 hybrid peptides derived from human immunodeficiency virus (HIV) type 1 gp120: Relation to specificity of peptide-induced anti-HIV neutralizing antibodies

Abstract

ASJC Scopus subject areas

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