Abstract
Female meiosis is unique in that an asymmetrically positioned meiotic spindle expels chromosomes into tiny, non-developing polar bodies. The extrusion of chromosomes into polar bodies is always mediated by meiotic spindles that are attached to the oocyte cortex by one pole. The asymmetric, cortical positioning of the oocyte meiotic spindle preserves the volume and contents of the oocyte. Recent work in C. elegans and mouse has provided mechanistic details of spindle positioning in oocytes.
Original language | English (US) |
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Pages (from-to) | 78-84 |
Number of pages | 7 |
Journal | Current Opinion in Cell Biology |
Volume | 23 |
Issue number | 1 |
DOIs | |
State | Published - Feb 2011 |
ASJC Scopus subject areas
- Cell Biology